4.6 Review

Bio-inspired wettability patterns for biomedical applications

Journal

MATERIALS HORIZONS
Volume 8, Issue 1, Pages 124-144

Publisher

ROYAL SOC CHEMISTRY
DOI: 10.1039/d0mh01293a

Keywords

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Funding

  1. National Key Research and Development Program of China [2020YFA090035]
  2. National Natural Science Foundation of China [61927805]
  3. Natural Science Foundation of Jiangsu [BE2018707]
  4. China Postdoctoral Science Foundation [2019M663090]

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This review provides a general summary of bio-inspired wettability patterns, including the design principles, fabrication methods, and practical applications in the biomedical field.
Benefiting from the remarkable wettability heterogeneity, bio-inspired wettability patterns present a progressive and versatile platform for manipulating and patterning liquids, which provides an emerging strategy for operating liquid samples with crucial values in biomedical applications. In this review, we present a general summary of bio-inspired wettability patterns. After a compendious introduction of natural wettability phenomena and their underlying mechanisms, we summarize the general design principles and fabrication methods for preparing artificial wettability materials. Next, we shift to patterned surface wettability with an emphasis on the fabrication approaches. Then, we discuss in detail the various practical applications of wettability patterns in the biomedical field, including cell culture, drug screening and biosensors. Critical thinking about the current challenges and future outlook is also provided. We believe that this review would propel the prosperous development of bio-inspired wettability patterns to flourish in the field of biomedical engineering.

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