Characterization of microneedles and microchannels for enhanced transdermal drug delivery

Microneedle (MN)-based technologies are currently one of the most innovative approaches that are being extensively investigated for transdermal delivery of low molecular weight drugs, biotherapeutic agents and vaccines. Extensive research reports, describing the fabrication and applications of different types of MNs, can be readily found in the literature. Effective characterization tools to evaluate the quality and performance of the MNs as well as for determination of the dimensional and kinetic properties of the microchannels created in the skin, are an essential and critical part of MN-based research. This review paper provides a comprehensive account of all such tools and techniques.

Automated summary

This review paper discusses the innovative research progress of microneedle technology in transdermal delivery of drugs, biotherapeutic agents, and vaccines, and provides a comprehensive introduction to the important tools and techniques for evaluating microneedle performance and skin microchannel characteristics.