Journal
CHEMICAL COMMUNICATIONS
Volume 57, Issue 4, Pages 480-483Publisher
ROYAL SOC CHEMISTRY
DOI: 10.1039/d0cc07292c
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Funding
- National Natural Science Foundation of China [21775133]
- Hunan Provincial Natural Science Foundation [2018JJ2385]
- Scientific Research Fund of Hunan Provincial Education Department [19A479]
- Degree & Postgraduate Education Reform Project of Hunan Province [CX20190483, XDCX2020B115]
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A novel water-soluble near-infrared fluorescent probe QX-P with simple synthesis has been developed, showing high sensitivity and selectivity to ALP. The probe is able to visualize ALP activity in four cell lines and real-time image ALP activity during the diagnosis and treatment of diabetes in mice.
A novel water-soluble near-infrared fluorescent probe named QX-P with simple synthesis is developed. QX-P has high sensitivity and selectivity to ALP. Moreover, the probe can not only visualize ALP activity in four cell lines, but also real-time image ALP activity during the diagnosis and treatment of diabetes in mice.
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