Journal
ALLERGY & RHINOLOGY
Volume 12, Issue -, Pages -Publisher
SAGE PUBLICATIONS INC
DOI: 10.1177/2152656720988565
Keywords
cryoablation; cryosurgery; cryosurgical ablation; posterior nasal nerve; rhinitis; rhinorrhea; congestion
Categories
Ask authors/readers for more resources
The study demonstrated the effectiveness of cryoablation of the PNN in improving symptoms of chronic rhinitis, with patients experiencing sustained improvement over a year and reducing the need for nasal sprays.
Background Chronic rhinitis is a common condition generally treated with medical therapies. However, 10-22% of patients are refractory to medical therapies. A cryotherapy handheld device targeting the postganglionic nerve fibers of the posterior nasal nerve (PNN) now serves as an additional option for therapy. This study evaluates the efficacy of the cryosurgical ablation device of the PNN in the clinic setting. Methods This was a prospective single-arm trial of 24 adult patients at seven locations within a large health maintenance organization. Patients with chronic rhinitis that failed medical therapy were offered an in-office cryoablation of PNN. Patients completed the Total Nasal Symptom Score (TNSS) questionnaire consisting of 5 items reported based on the previous 12 hours and 2 weeks at the following time points: pre-treatment, 30 days, 90 days and 1 year post-treatment. Results Following cryoablation of the PNN, the TNSS 12-hour symptom score improved from 6.92 (+/- 2.9) to 3.17 (+/- 2.4, P < 0.001) at 30 days, 2.92 (+/- 1.4, P < 0.001) at 90 days and 3.08 (+/- 2.6, P < 0.001) at 1 year post treatment. Similar results were noted for the 2 weeks scores improving from 7.75 (+/- 3.1) to 3.79 (+/- 2.1, P < 0.001) at 30 days, 3.88 (+/- 1.9, P < 0.001) at 90 days and 3.76 (+/- 2.1, P < 0.001) at 1 year post-treatment. 64.7% of respondents stated the procedure decreased or eliminated nasal sprays. Conclusions Our independent evaluation of cryoablation of the PNN shows improvement in nasal symptoms over a 1 year period and is consistent with other published data.
Authors
I am an author on this paper
Click your name to claim this paper and add it to your profile.
Reviews
Recommended
No Data Available