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GENES & DEVELOPMENT (2013)
The histone H3.3K27M mutation in pediatric glioma reprograms H3K27 methylation and gene expression
Kui-Ming Chan et al.
GENES & DEVELOPMENT (2013)
Overexpression of the chromatin remodeler death-domain-associated protein in prostate cancer is an independent predictor of early prostate-specific antigen recurrence
Maria Christina Tsourlakis et al.
HUMAN PATHOLOGY (2013)
Death Domain-associated Protein DAXX Promotes Ovarian Cancer Development and Chemoresistance
Wei-Wei Pan et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2013)
A two-step mechanism for epigenetic specification of centromere identity and function
Daniele Fachinetti et al.
NATURE CELL BIOLOGY (2013)
Distinct H3F3A and H3F3B driver mutations define chondroblastoma and giant cell tumor of bone
Sam Behjati et al.
NATURE GENETICS (2013)
The genetic landscape of high-risk neuroblastoma
Trevor J. Pugh et al.
NATURE GENETICS (2013)
H2A.Z-dependent crosstalk between enhancer and promoter regulates Cyclin D1 expression
M. Dalvai et al.
ONCOGENE (2013)
Immunopositivity for Histone MacroH2A1 Isoforms Marks Steatosis-Associated Hepatocellular Carcinoma
Francesca Rappa et al.
PLOS ONE (2013)
Modulation of HJURP (Holliday Junction-Recognizing Protein) Levels Is Correlated with Glioblastoma Cells Survival
Valeria Valente et al.
PLOS ONE (2013)
Prognostic Significance of EDN/RB, HJURP, p60/CAF-1 and PDLI4, Four New Markers in High-Grade Gliomas
Marie de Tayrac et al.
PLOS ONE (2013)
TERT promoter mutations occur frequently in gliomas and a subset of tumors derived from cells with low rates of self-renewal
Patrick J. Killela et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2013)
Inhibition of PRC2 Activity by a Gain-of-Function H3 Mutation Found in Pediatric Glioblastoma
Peter W. Lewis et al.
SCIENCE (2013)
Developmental roles of histone H3 variants and their chaperones
Dan Filipescu et al.
TRENDS IN GENETICS (2013)
Prognostic value of centromere protein-A expression in patients with epithelial ovarian cancer
Jun-Jun Qiu et al.
TUMOR BIOLOGY (2013)
MacroH2A histone variants act as a barrier upon reprogramming towards pluripotency
Alexandre Gaspar-Maia et al.
NATURE COMMUNICATIONS (2013)
Histone H3.3 Mutations Drive Pediatric Glioblastoma through Upregulation of MYCN
Lynn Bjerke et al.
CANCER DISCOVERY (2013)
Facilitates Chromatin Transcription Complex Is an Accelerator'' of Tumor Transformation and Potential Marker and Target of Aggressive Cancers
Henry Garcia et al.
CELL REPORTS (2013)
Macrohistone Variants Preserve Cell Identity by Preventing the Gain of H3K4me2 during Reprogramming to Pluripotency
Maria J. Barrero et al.
CELL REPORTS (2013)
Comprehensive Analysis of Transcriptome Variation Uncovers Known and Novel Driver Events in T-Cell Acute Lymphoblastic Leukemia
Zeynep Kalender Atak et al.
PLOS GENETICS (2013)
H2A.Z Acidic Patch Couples Chromatin Dynamics to Regulation of Gene Expression Programs during ESC Differentiation
Vidya Subramanian et al.
PLOS GENETICS (2013)
K27M mutation in histone H3.3 defines clinically and biologically distinct subgroups of pediatric diffuse intrinsic pontine gliomas
Dong-Anh Khuong-Quang et al.
ACTA NEUROPATHOLOGICA (2012)
Hotspot Mutations in H3F3A and IDH1 Define Distinct Epigenetic and Biological Subgroups of Glioblastoma
Dominik Sturm et al.
CANCER CELL (2012)
Histone H2A.Z prepares the prostate specific antigen (PSA) gene for androgen receptor-mediated transcription and is upregulated in a model of prostate cancer progression
Deanna Dryhurst et al.
CANCER LETTERS (2012)
Cdk Activity Couples Epigenetic Centromere Inheritance to Cell Cycle Progression
Mariana C. C. Silva et al.
DEVELOPMENTAL CELL (2012)
The histone variant macroH2A1.1 is recruited to DSBs through a mechanism involving PARP1
Chang Xu et al.
FEBS LETTERS (2012)
ATRX-mediated chromatin association of histone variant macroH2A1 regulates α-globin expression
Kajan Ratnakumar et al.
GENES & DEVELOPMENT (2012)
Acetylation of H2A.Z is a key epigenetic modification associated with gene deregulation and epigenetic remodeling in cancer
Fatima Valdes-Mora et al.
GENOME RESEARCH (2012)
Association of Age at Diagnosis and Genetic Mutations in Patients With Neuroblastoma
Nai-Kong V. Cheung et al.
JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION (2012)
Histone variant macroH2A marks embryonic differentiation in vivo and acts as an epigenetic barrier to induced pluripotency
Vincent Pasque et al.
JOURNAL OF CELL SCIENCE (2012)
Independence of Repressive Histone Marks and Chromatin Compaction during Senescent Heterochromatic Layer Formation
Tamir Chandra et al.
MOLECULAR CELL (2012)
Histone H2A.Z Controls a Critical Chromatin Remodeling Step Required for DNA Double-Strand Break Repair
Ye Xu et al.
MOLECULAR CELL (2012)
Expression and prognostic significance of centromere protein A in human lung adenocarcinoma
Qing Wu et al.
LUNG CANCER (2012)
Driver mutations in histone H3.3 and chromatin remodelling genes in paediatric glioblastoma
Jeremy Schwartzentruber et al.
NATURE (2012)
Sequencing of neuroblastoma identifies chromothripsis and defects in neuritogenesis genes
Jan J. Molenaar et al.
NATURE (2012)
Somatic histone H3 alterations in pediatric diffuse intrinsic pontine gliomas and non-brainstem glioblastomas
Gang Wu et al.
NATURE GENETICS (2012)
Splicing switch of an epigenetic regulator by RNA helicases promotes tumor-cell invasiveness
Etienne Dardenne et al.
NATURE STRUCTURAL & MOLECULAR BIOLOGY (2012)
Decrease of p400 ATPase complex and loss of H2A.Z within the p21 promoter occur in senescent IMR-90 human fibroblasts
Kangmoon Lee et al.
MECHANISMS OF AGEING AND DEVELOPMENT (2012)
The CHR promoter element controls cell cycle-dependent gene transcription and binds the DREAM and MMB complexes
Gerd A. Mueller et al.
NUCLEIC ACIDS RESEARCH (2012)
H3K4 demethylation by Jarid1a and Jarid1b contributes to retinoblastoma-mediated gene silencing during cellular senescence
Agustin Chicas et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2012)
The cBio Cancer Genomics Portal: An Open Platform for Exploring Multidimensional Cancer Genomics Data
Ethan Cerami et al.
CANCER DISCOVERY (2012)
A Combination of H2A.Z and H4 Acetylation Recruits Brd2 to Chromatin during Transcriptional Activation
Ryan Draker et al.
PLOS GENETICS (2012)
H2A.Z landscapes and dual modifications in pluripotent and multipotent stem cells underlie complex genome regulatory functions
Manching Ku et al.
GENOME BIOLOGY (2012)
Centromere protein-A, an essential centromere protein, is a prognostic marker for relapse in estrogen receptor-positive breast cancer
Susan L. McGovern et al.
BREAST CANCER RESEARCH (2012)
Structures of human nucleosomes containing major histone H3 variants
Hiroaki Tachiwana et al.
ACTA CRYSTALLOGRAPHICA SECTION D-BIOLOGICAL CRYSTALLOGRAPHY (2011)
Oncometabolite 2-Hydroxyglutarate Is a Competitive Inhibitor of α-Ketoglutarate-Dependent Dioxygenases
Wei Xu et al.
CANCER CELL (2011)
Epigenetic Centromere Propagation and the Nature of CENP-A Nucleosomes
Ben E. Black et al.
CELL (2011)
Hallmarks of Cancer: The Next Generation
Douglas Hanahan et al.
CELL (2011)
Histone variant macroH2A confers resistance to nuclear reprogramming
Vincent Pasque et al.
EMBO JOURNAL (2011)
The oncometabolite 2-hydroxyglutarate inhibits histone lysine demethylases
Rasheduzzaman Chowdhury et al.
EMBO REPORTS (2011)
Structure of a CENP-A-histone H4 heterodimer in complex with chaperone HJURP
Hao Hu et al.
GENES & DEVELOPMENT (2011)
QKI-Mediated Alternative Splicing of the Histone Variant MacroH2A1 Regulates Cancer Cell Proliferation
Leonid Novikov et al.
MOLECULAR AND CELLULAR BIOLOGY (2011)
Dynamics of Histone H3 Deposition In Vivo Reveal a Nucleosome Gap-Filling Mechanism for H3.3 to Maintain Chromatin Integrity
Dominique Ray-Gallet et al.
MOLECULAR CELL (2011)
Histone Methylation by PRC2 Is Inhibited by Active Chromatin Marks
Frank W. Schmitges et al.
MOLECULAR CELL (2011)
Crystal structure of the human centromeric nucleosome containing CENP-A
Hiroaki Tachiwana et al.
NATURE (2011)
Recognition of enhancer element-specific histone methylation by TIP60 in transcriptional activation
Kwang Won Jeong et al.
NATURE STRUCTURAL & MOLECULAR BIOLOGY (2011)
USP10 deubiquitylates the histone variant H2A.Z and both are required for androgen receptor-mediated gene activation
Ryan Draker et al.
NUCLEIC ACIDS RESEARCH (2011)
ShRNA-Targeted Centromere Protein A Inhibits Hepatocellular Carcinoma Growth
Yongmei Li et al.
PLOS ONE (2011)
Altered Telomeres in Tumors with ATRX and DAXX Mutations
Christopher M. Heaphy et al.
SCIENCE (2011)
DAXX/ATRX, MEN1, and mTOR Pathway Genes Are Frequently Altered in Pancreatic Neuroendocrine Tumors
Yuchen Jiao et al.
SCIENCE (2011)
Function and metabolism of sirtuin metabolite O-acetyl-ADP-ribose
Lei Tong et al.
BIOCHIMICA ET BIOPHYSICA ACTA-PROTEINS AND PROTEOMICS (2010)
Distinct Factors Control Histone Variant H3.3 Localization at Specific Genomic Regions
Aaron D. Goldberg et al.
CELL (2010)
ATR-X Syndrome Protein Targets Tandem Repeats and Influences Allele-Specific Expression in a Size-Dependent Manner
Martin J. Law et al.
CELL (2010)
H2A.Z overexpression promotes cellular proliferation of breast cancer cells
Amy Svotelis et al.
CELL CYCLE (2010)
The histone variant macroH2A1 marks repressed autosomal chromatin, but protects a subset of its target genes from silencing
Matthew J. Gamble et al.
GENES & DEVELOPMENT (2010)
Proliferation of aneuploid human cells is limited by a p53-dependent mechanism
Sarah L. Thompson et al.
JOURNAL OF CELL BIOLOGY (2010)
The Chromatin Remodeling Factor SRCAP Modulates Expression of Prostate Specific Antigen and Cellular Proliferation in Prostate Cancer Cells
Artur Slupianek et al.
JOURNAL OF CELLULAR PHYSIOLOGY (2010)
Genome-Wide Distribution of MacroH2A1 Histone Variants in Mouse Liver Chromatin
Lakshmi N. Changolkar et al.
MOLECULAR AND CELLULAR BIOLOGY (2010)
The histone variant macroH2A suppresses melanoma progression through regulation of CDK8
Avnish Kapoor et al.
NATURE (2010)
Selective inhibition of BET bromodomains
Panagis Filippakopoulos et al.
NATURE (2010)
Nucleosome dynamics define transcriptional enhancers
Housheng Hansen He et al.
NATURE GENETICS (2010)
Daxx is an H3.3-specific histone chaperone and cooperates with ATRX in replication-independent chromatin assembly at telomeres
Peter W. Lewis et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2010)
Histone variant macroH2A1 deletion in mice causes female-specific steatosis
Mathieu Boulard et al.
EPIGENETICS & CHROMATIN (2010)
The expression level of HJURP has an independent prognostic impact and predicts the sensitivity to radiotherapy in breast cancer
Zhi Hu et al.
BREAST CANCER RESEARCH (2010)
Characterization of the histone H2A.Z-1 and H2A.Z-2 isoforms in vertebrates
Deanna Dryhurst et al.
BMC BIOLOGY (2009)
The evolutionary differentiation of two histone H2A.Z variants in chordates (H2A.Z-1 and H2A.Z-2) is mediated by a stepwise mutation process that affects three amino acid residues
Jose M. Eirin-Lopez et al.
BMC EVOLUTIONARY BIOLOGY (2009)
HJURP Is a Cell-Cycle-Dependent Maintenance and Deposition Factor of CENP-A at Centromeres
Elaine M. Dunleavy et al.
CELL (2009)
Centromere-Specific Assembly of CENP-A Nucleosomes Is Mediated by HJURP
Daniel R. Foltz et al.
CELL (2009)
Principles of Cancer Therapy: Oncogene and Non-oncogene Addiction
Ji Luo et al.
CELL (2009)
Histone H2A.Z is essential for estrogen receptor signaling
Nicolas Gevry et al.
GENES & DEVELOPMENT (2009)
H3.3/H2A.Z double variant-containing nucleosomes mark 'nucleosome-free regions' of active promoters and other regulatory regions
Chunyuan Jin et al.
NATURE GENETICS (2009)
A macrodomain-containing histone rearranges chromatin upon sensing PARP1 activation
Gyula Timinszky et al.
NATURE STRUCTURAL & MOLECULAR BIOLOGY (2009)
The histone variant macroH2A is an epigenetic regulator of key developmental genes
Marcus Buschbeck et al.
NATURE STRUCTURAL & MOLECULAR BIOLOGY (2009)
Cooperative action of TIP48 and TIP49 in H2A.Z exchange catalyzed by acetylation of nucleosomal H2A
Jongkyu Choi et al.
NUCLEIC ACIDS RESEARCH (2009)
The p400/Tip60 ratio is critical for colorectal cancer cell proliferation through DNA damage response pathways
L. Mattera et al.
ONCOGENE (2009)
Histone macroH2A isoforms predict the risk of lung cancer recurrence
J. C. Sporn et al.
ONCOGENE (2009)
The Euchromatic and Heterochromatic Landscapes Are Shaped by Antagonizing Effects of Transcription on H2A.Z Deposition
Sara Hardy et al.
PLOS GENETICS (2009)
H2AZ Is Enriched at Polycomb Complex Target Genes in ES Cells and Is Necessary for Lineage Commitment
Menno P. Creyghton et al.
CELL (2008)
Genomic analysis of estrogen cascade reveals histone variant H2A.Z associated with breast cancer progression
Sujun Hua et al.
MOLECULAR SYSTEMS BIOLOGY (2008)
An integrated genomic analysis of human glioblastoma Multiforme
D. Williams Parsons et al.
SCIENCE (2008)
Regulation of replication fork progression through histone supply and demand
Anja Groth et al.
SCIENCE (2007)
Activation of holliday junction-recognizing protein involved in the chromosomal stability and immortality of cancer cells
Tatsuya Kato et al.
CANCER RESEARCH (2007)
Nucleosome stability mediated by histone variants H3.3 and H2A.Z
Chunyuan Jin et al.
GENES & DEVELOPMENT (2007)
Poly(ADP-ribose) polymerase 1 is inhibited by a histone H2A variant, MacroH2A, and contributes to silencing of the inactive X chromosome
Dmitri A. Nusinow et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2007)
Propagation of centromeric chromatin requires exit from mitosis
Lars E. T. Jansen et al.
JOURNAL OF CELL BIOLOGY (2007)
H2A.Z contributes to the unique 3D structure of the centromere
Ian K. Greaves et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2007)
Developmental changes in histone macroH2A1-mediated gene regulation
Lakshmi N. Changolkar et al.
MOLECULAR AND CELLULAR BIOLOGY (2007)
Monoubiquitylation of H2A.Z distinguishes its association with euchromatin or facultative heterochromatin
Elizabeth Sarcinella et al.
MOLECULAR AND CELLULAR BIOLOGY (2007)
The histone variant mH2A1.1 interferes with transcription by down-regulating PARP-1 enzymatic activity
Khalid Ouararhni et al.
GENES & DEVELOPMENT (2006)
Structure of a human ASF1a-HIRA complex and insights into specificity of histone chaperone complex assembly
Yong Tang et al.
NATURE STRUCTURAL & MOLECULAR BIOLOGY (2006)
Expression patterns and post-translational modifications associated with mammalian histone H3 variants
SB Hake et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2006)
The menin tumor suppressor protein is an essential oncogenic cofactor for MLL-associated leukemogenesis
A Yokoyama et al.
CELL (2005)
Structural characterization of the histone variant macroH2A
S Chakravarthy et al.
MOLECULAR AND CELLULAR BIOLOGY (2005)
Splicing regulates NAD metabolite binding to histone macroH2A
G Kustatscher et al.
NATURE STRUCTURAL & MOLECULAR BIOLOGY (2005)
CENP-A is required for accurate chromosome segregation and sustained kinetochore association of BubR1
V Régnier et al.
MOLECULAR AND CELLULAR BIOLOGY (2005)
Formation of MacroH2A-containing senescence-associated heterochromatin foci and senescence driven by ASF1a and HIRA
RG Zhang et al.
DEVELOPMENTAL CELL (2005)
Histone H3.1 and H3.3 complexes mediate nucleosome assembly pathways dependent or independent of DNA synthesis
H Tagami et al.
CELL (2004)
Large-scale meta-analysis of cancer microarray data identifies common transcriptional profiles of neoplastic transformation and progression
DR Rhodes et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2004)
MYC recruits the TIP60 histone acetyltransferase complex to chromatin
SR Frank et al.
EMBO REPORTS (2003)
Gene expression profiles of human breast cancer progression
XJ Ma et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2003)
Human Asf1 and CAF-1 interact and synergize in a repair-coupled nucleosome assembly pathway
JA Mello et al.
EMBO REPORTS (2002)
Histone variant H2A.Z is required for early mammalian development
R Faast et al.
CURRENT BIOLOGY (2001)
MACROH2A2, a new member of the MACROH2A core histone family
C Costanzi et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2001)
Chromatin assembly at kinetochores is uncoupled from DNA replication
RD Shelby et al.
JOURNAL OF CELL BIOLOGY (2000)
A CAF-1-PCNA-mediated chromatin assembly pathway triggered by sensing DNA damage
JG Moggs et al.
MOLECULAR AND CELLULAR BIOLOGY (2000)
Early disruption of centromeric chromatin organization in centromere protein A (Cenpa) null mice
EV Howman et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2000)