Journal
CHEMICAL SCIENCE
Volume 12, Issue 5, Pages 1791-1795Publisher
ROYAL SOC CHEMISTRY
DOI: 10.1039/d0sc04399k
Keywords
-
Categories
Funding
- National Natural Science Foundation of China [21971201]
- Natural Science Basic Research Plan in Shaanxi Province of China [2019JM-299]
- Key Laboratory Construction Program of Xi'an Municipal Bureau of Science and Technology [201805056ZD7CG40]
Ask authors/readers for more resources
A visible light-induced palladium-catalyzed Dowd-Beckwith ring expansion/C-C bond formation cascade has been successfully developed to access a variety of six to nine-membered beta-alkenylated cyclic ketones with a quaternary carbon center under mild conditions. In addition to styrenes, electron-rich alkenes like silyl enol ethers and enamides are also compatible substrates, providing the desired beta-alkylated cyclic ketones in moderate to good yields.
A visible-light-induced palladium-catalyzed Dowd-Beckwith ring expansion/C-C bond formation cascade is described. A range of six to nine-membered beta-alkenylated cyclic ketones possessing a quaternary carbon center were accessed under mild conditions. Besides styrenes, the electron-rich alkenes such as silyl enol ethers and enamides were also compatible, providing the desired beta-alkylated cyclic ketones in moderate to good yields.
Authors
I am an author on this paper
Click your name to claim this paper and add it to your profile.
Reviews
Recommended
No Data Available
Share Paper
