Modern approaches towards the synthesis of geminal difluoroalkyl groups

This review will cover the importance of and most recent approaches toward geminal difluoroalkyl groups. Transition metal-mediated, photochemical, organocatalytic, and other methods as well as their mechanistic implications will be discussed, with special emphasis on applications to biologically-relevant compounds.

Automated summary

This review covers the importance of and most recent approaches toward geminal difluoroalkyl groups, with special emphasis on applications to biologically-relevant compounds. Various methods such as transition metal-mediated, photochemical, and organocatalytic approaches will be discussed along with their mechanistic implications.