pH-Sensitive nanogels for drug delivery in cancer therapy

As a commonly used treatment method for cancer, chemotherapy is greatly limited by the side effects of chemotherapy drugs and the multiple drug resistance that develops. Nanogels are considered ideal drug carriers due to their high stability, high water content and excellent drug loading capacities. To achieve more precise and intelligent drug delivery in tumor tissues, various environmentally responsive nanogels have been widely developed. Compared to normal tissue, tumor tissue exhibits a lower pH value. Therefore, the pH gradients between the tumor microenvironment and the normal physiological environment can be used to design pH-sensitive nanogels to regulate the delivery and release of antitumor drugs. This article mainly introduces the application of pH-sensitive nanogels in cancer treatment, hoping to provide a reference for the development of cancer treatment.

Automated summary

Nanogels are considered ideal drug carriers for cancer treatment due to their high stability, water content, and drug loading capacities. pH-sensitive nanogels, which utilize the lower pH value in tumor tissue, have shown potential for more precise drug delivery and release in cancer treatment.