4.6 Article

ATP mediated stimuli responsive supramolecular assembly

Journal

SOFT MATTER
Volume 17, Issue 5, Pages 1178-1183

Publisher

ROYAL SOC CHEMISTRY
DOI: 10.1039/d0sm02274h

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Careful design can integrate chemical enrichment, stimuli responsiveness, and targeted delivery within compartmentalized models to enhance therapeutic efficacy.
Adenosine triphosphate has been employed as a biomolecular building block to fabricate pH and enzyme responsive compartmentalized supramolecular assemblies sequestering silver nanoparticles (AgNPs) and doxorubicin in the core and increase the therapeutic efficacy. Detailed investigations reveal that meticulous design can integrate chemical enrichment, stimuli responsiveness and targeted delivery within compartmentalized models.

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