4.5 Review

Role of bone-forming agents in the management of osteoporosis

Journal

AGING CLINICAL AND EXPERIMENTAL RESEARCH
Volume 33, Issue 4, Pages 775-791

Publisher

SPRINGER
DOI: 10.1007/s40520-020-01708-8

Keywords

Osteoporosis; Osteoanabolic; Abaloparatide; Romosozumab; Teriparatide; Sequence

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Recent evidence supports the use of osteoanabolic therapy over anti-remodeling drugs for improving bone density and reducing fracture risk rapidly, especially in high-risk patients. This review discusses the latest research findings and the current status of osteoanabolic therapy for osteoporosis.
Recent evidence confirms the superiority of osteoanabolic therapy compared to anti-remodeling drugs for rapid improvement in bone density and fracture risk reduction, providing strong justification for the use of these anabolic agents as the initial therapy in high-risk patients, to be followed by anti-remodeling therapy. This review will highlight the results of recent studies and define the current status of osteoanabolic therapy for osteoporosis.

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