4.7 Article

CovidCTNet: an open-source deep learning approach to diagnose covid-19 using small cohort of CT images

Journal

NPJ DIGITAL MEDICINE
Volume 4, Issue 1, Pages -

Publisher

NATURE PORTFOLIO
DOI: 10.1038/s41746-021-00399-3

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The article discusses the importance of early and accurate diagnosis of Covid-19, as well as the pros and cons of RT-PCR and CT imaging. A new open-source framework called CovidCTNet is introduced to improve the accuracy of CT imaging detection of Covid-19 to 95%.
Coronavirus disease 2019 (Covid-19) is highly contagious with limited treatment options. Early and accurate diagnosis of Covid-19 is crucial in reducing the spread of the disease and its accompanied mortality. Currently, detection by reverse transcriptase-polymerase chain reaction (RT-PCR) is the gold standard of outpatient and inpatient detection of Covid-19. RT-PCR is a rapid method; however, its accuracy in detection is only similar to 70-75%. Another approved strategy is computed tomography (CT) imaging. CT imaging has a much higher sensitivity of similar to 80-98%, but similar accuracy of 70%. To enhance the accuracy of CT imaging detection, we developed an open-source framework, CovidCTNet, composed of a set of deep learning algorithms that accurately differentiates Covid-19 from community-acquired pneumonia (CAP) and other lung diseases. CovidCTNet increases the accuracy of CT imaging detection to 95% compared to radiologists (70%). CovidCTNet is designed to work with heterogeneous and small sample sizes independent of the CT imaging hardware. To facilitate the detection of Covid-19 globally and assist radiologists and physicians in the screening process, we are releasing all algorithms and model parameter details as open-source. Open-source sharing of CovidCTNet enables developers to rapidly improve and optimize services while preserving user privacy and data ownership.

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