Journal
CRYSTENGCOMM
Volume 23, Issue 5, Pages 1099-1109Publisher
ROYAL SOC CHEMISTRY
DOI: 10.1039/d0ce01533d
Keywords
-
Categories
Funding
- Fundacao para a Ciencia e a Tecnologia (FCT, Portugal) [UIDB/00100/2020, UIDP/00100/2020, UID/QUI/00100/2019, PTDC/QUI-OUT/30988/2017, CEECIND2018, 57/2016]
- FEDER, Portugal 2020 [LISBOA-01-0145-FEDER-030988]
- FEDER, Lisboa 2020 [LISBOA-01-0145-FEDER-030988]
- Fundação para a Ciência e a Tecnologia [PTDC/QUI-OUT/30988/2017] Funding Source: FCT
Ask authors/readers for more resources
Mechanochemistry has been playing a significant role in chemistry in recent years, with potential in a wide variety of reactions contributing to sustainable chemistry and leading to lower reaction time, higher selectivity, and novel reactivity. New solid forms of pipemidic acid obtained by mechanochemistry demonstrate its importance in antibiotic production and metal-organic framework synthesis.
Mechanochemistry has been assuming a major role in chemistry over the last years. Its potential in a wide variety of reactions is undeniable nowadays, contributing to sustainable chemistry and, at the same time, leading to lower reaction time, higher selectivity and novel reactivity. Herein we disclose new solid forms of pipemidic acid, an antibiotic against which bacteria have been developing resistance mechanisms, obtained by mechanochemistry. These forms are molecular salts with glycolic, oxalic and (R)- and (S)-camphorsulfonic acids, as well as a Cu(II) complex exhibiting a 1D hydrogen bonded network. To prove the importance of the technique, we present here also the rapid and high yielding mechanochemical synthesis of a previously reported Ag metal-organic framework with pipemidic acid.
Authors
I am an author on this paper
Click your name to claim this paper and add it to your profile.
Reviews
Recommended
No Data Available