Journal
JOURNAL OF RESEARCH OF THE NATIONAL INSTITUTE OF STANDARDS AND TECHNOLOGY
Volume 126, Issue -, Pages -Publisher
NATL INST STANDARDS & TECHNOLOGY-NIST
DOI: 10.6028/jres.126.001
Keywords
DNA nanofabrication; DNA origami; self-assembly
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Despite the simplicity of design and assembly of DNA origami, the tools and methods for designing new structures are not as well codified as mature technologies. This document aims to provide a step-by-step guide to designing DNA origami nanostructures using current state-of-the-art tools.
While the design and assembly of DNA origami are straightforward, its relative novelty as a nanofabrication technique means that the tools and methods for designing new structures have not been codified as well as they have for more mature technologies, such as integrated circuits. While design approaches cannot be truly formalized until design-property relationships are fully understood, this document attempts to provide a step-by-step guide to designing DNA origami nanostructures using the tools available at the current state of the art.
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