Journal
ANNALS OF PALLIATIVE MEDICINE
Volume 10, Issue 1, Pages 340-349Publisher
AME PUBL CO
DOI: 10.21037/apm-20-2267
Keywords
31-40 years; women; circadian rhythm disorders; body composition; insulin resistance
Categories
Ask authors/readers for more resources
The study demonstrates that circadian rhythm disorders can lead to decreased body water, muscle mass, and insulin resistance, as well as increased visceral fat in women aged 31-40, potentially increasing the risk of cardiovascular diseases and diabetes.
Background: Circadian rhythm disorder caused by lack of sleep, day-night reversal, or staying up late, can cause irreparable damage to the body, a significant increase in both the systolic and diastolic blood pressure of women in this age bracket. The purpose of this study was to investigate the effects of circadian disruption on body composition and insulin resistance in women aged 31-40 years. Methods: Thirty female with circadian rhythm disorder and employed of the Foot Bath Club in Qufu city were selected as the research subjects, and a body composition analyzer was used to test the subjects' body composition using bioelectrical impedance analysis. Serum melatonin (MT) levels were determined by enzyme-linked immunosorbent assay (ELISA), and blood glucose and insulin levels were detected by glucose oxidase and chemiluminescence assays, respectively. Results: The results showed that circadian rhythm disorder caused a rise in blood pressure, whereas body water, especially lower limb water and intra- and extracellular fluid, decreased significantly. Circadian disruption also resulted in decreased muscle mass, protein quality, and melatonin production, but increased visceral fat levels and insulin resistance. Conclusions: This study has demonstrated that circadian rhythm disorders are responsible for changes in body composition, melatonin levels, and insulin resistance in women aged 31-40 years and may be a risk factor for cardiovascular disease and diabetes.
Authors
I am an author on this paper
Click your name to claim this paper and add it to your profile.
Reviews
Recommended
No Data Available