Related references
Note: Only part of the references are listed.Synergistic anti-breast cancer effect of pulsatilla saponin D and camptothecin through interrupting autophagic-lysosomal function and promoting p62-mediated ubiquitinated protein aggregation
Kai Wang et al.
CARCINOGENESIS (2020)
Ubiquitomics: An Overview and Future
George Vere et al.
BIOMOLECULES (2020)
TFEB-mediated lysosomal biogenesis and lysosomal drug sequestration confer resistance to MEK inhibition in pancreatic cancer
Ben Zhao et al.
CELL DEATH DISCOVERY (2020)
Cancer Cells Upregulate NRF2 Signaling to Adapt to Autophagy Inhibition
Christina G. Towers et al.
DEVELOPMENTAL CELL (2019)
Lysosome imaging in cancer cells by pyrene-benzothiazolium dyes: An alternative imaging approach for LAMP-1 expression based visualization methods to avoid background interference
Chathura S. Abeyvvickrama et al.
BIOORGANIC CHEMISTRY (2019)
The Lysosomal Sequestration of Tyrosine Kinase Inhibitors and Drug Resistance
Eliska Ruzickova et al.
BIOMOLECULES (2019)
Quantitation of Lysosomal Trapping of Basic Lipophilic Compounds Using In Vitro Assays and In Silico Predictions Based on the Determination of the Full pH Profile of the Endo-/Lysosomal System in Rat Hepatocytes
Maximilian V. Schmitt et al.
DRUG METABOLISM AND DISPOSITION (2019)
HEPES activates a MiT/TFE-dependent lysosomal-autophagic gene network in cultured cells: A call for caution
Marc J. Tol et al.
AUTOPHAGY (2018)
Systems analysis of intracellular pH vulnerabilities for cancer therapy
Erez Persi et al.
NATURE COMMUNICATIONS (2018)
Lysosomotropic drugs activate TFEB via lysosomal membrane fluidization and consequent inhibition of mTORC1 activity
Benny Zhitomirsky et al.
CELL DEATH & DISEASE (2018)
Lysosomotropism depends on glucose: a chloroquine resistance mechanism
Laura E. Gallagher et al.
CELL DEATH & DISEASE (2017)
Lysosomal adaptation: How cells respond to lysosomotropic compounds
Shuyan Lu et al.
PLOS ONE (2017)
Inhibition of cholesterol metabolism underlies synergy between mTOR pathway inhibition and chloroquine in bladder cancer cells
M. A. King et al.
ONCOGENE (2016)
Lysosomal Sequestration Determines Intracellular Imatinib Levels
Herman Burger et al.
MOLECULAR PHARMACOLOGY (2015)
Phase I clinical trial and pharmacodynamic evaluation of combination hydroxychloroquine and doxorubicin treatment in pet dogs treated for spontaneously occurring lymphoma
Rebecca A. Barnard et al.
AUTOPHAGY (2014)
Acidic extracellular pH neutralizes the autophagy-inhibiting activity of chloroquine
Paola Pellegrini et al.
AUTOPHAGY (2014)
STAT3-Mediated Autophagy Dependence Identifies Subtypes of Breast Cancer Where Autophagy Inhibition Can Be Efficacious
Paola Maycotte et al.
CANCER RESEARCH (2014)
A lysosome-to-nucleus signalling mechanism senses and regulates the lysosome via mTOR and TFEB
Carmine Settembre et al.
EMBO JOURNAL (2012)
Clinicopathological Significance of Mesothelin Expression in Invasive Breast Cancer
L. Wang et al.
JOURNAL OF INTERNATIONAL MEDICAL RESEARCH (2012)
Lysosomotropic Properties of Weakly Basic Anticancer Agents Promote Cancer Cell Selectivity In Vitro
Rosemary A. Ndolo et al.
PLOS ONE (2012)
Pharmacokinetics, Pharmacodynamics, and Allometric Scaling of Chloroquine in a Murine Malaria Model
Brioni R. Moore et al.
ANTIMICROBIAL AGENTS AND CHEMOTHERAPY (2011)
Characterization of the CLEAR network reveals an integrated control of cellular clearance pathways
Michela Palmieri et al.
HUMAN MOLECULAR GENETICS (2011)
Drug Resistance and Cellular Adaptation to Tumor Acidic pH Microenvironment
Jonathan W. Wojtkowiak et al.
MOLECULAR PHARMACEUTICS (2011)
TFEB Links Autophagy to Lysosomal Biogenesis
Carmine Settembre et al.
SCIENCE (2011)
Lipophilic Cationic Drugs Increase the Permeability of Lysosomal Membranes in a Cell Culture System
Johannes Kornhuber et al.
JOURNAL OF CELLULAR PHYSIOLOGY (2010)
Quantitative modeling of selective lysosomal targeting for drug design
Stefan Trapp et al.
EUROPEAN BIOPHYSICS JOURNAL WITH BIOPHYSICS LETTERS (2008)
A novel assay reveals that weakly basic model compounds concentrate in lysosomes to an extent greater than pH-partitioning theory would predict
Muralikrishna Duvvuri et al.
MOLECULAR PHARMACEUTICS (2005)