Paediatric glaucoma in Hong Kong: a multicentre retrospective analysis of epidemiology, presentation, clinical interventions, and outcomes

Purpose: To document the epidemiology, presentation, clinical interventions, and outcomes of paediatric glaucoma in Hong Kong. Methods: This multicentre territory-wide retrospective study was performed by reviewing charts of patients with paediatric glaucoma in six clusters of the Hong Kong Hospital Authority and The Chinese University of Hong Kong from 2006 to 2015. Results: This study included 150 eyes of 98 patients with paediatric glaucoma (presenting age: 5.2 +/- 5.7 years). Of them, 35 eyes (23.3%) had primary congenital glaucoma, 22 eyes (14.7%) had juvenile open-angle glaucoma, and 93 eyes (62.0%) had secondary glaucoma. The most prevalent types of secondary glaucoma were lens-related after cataract extraction (18.0%), Axenfeld-Rieger anomaly (5.3%), uveitis (5.3%), Sturge-Weber syndrome (4.7%), and traumatic (3.3%). The most common clinical presentations were parental concerns (20.7%) including cloudy cornea (12.7%) and tearing/ photophobia (8.0%), followed by poor visual acuity (18.0%), high intraocular pressure (13.3%), and strabismus (6.0%). The follow-up duration was 8.46 +/- 6.51 years. Furthermore, 63.2% of eyes with primary glaucoma and 45.2% of eyes with secondary glaucoma were treated surgically. The final visual acuity was 0.90 +/- 0.98 LogMAR; intraocular pressure was 18.4 +/- 6.6 mm Hg; and number of glaucoma medications was 2.22 +/- 1.61. Conclusion: Primary congenital glaucoma was most prevalent, followed by juvenile open-angle glaucoma and aphakic glaucoma. Most eyes with primary glaucoma required surgical treatment. Parental concerns were important clinical presentations. Basic assessments by healthcare providers to identify glaucoma signs (eg, poor visual acuity, high intraocular pressure, and strabismus) warranted prompt referral to an ophthalmologist.

Automated summary

This retrospective study in Hong Kong documented the epidemiology, presentation, clinical interventions, and outcomes of paediatric glaucoma. It found that primary congenital glaucoma was the most prevalent, with primary glaucoma eyes often requiring surgical treatment. Parental concerns were identified as important clinical presentations for paediatric glaucoma.