4.7 Article

Single-Walled Carbon Nanotube Sensor Platform for the Study of Extracellular Analytes

Journal

ACS APPLIED NANO MATERIALS
Volume 4, Issue 1, Pages 33-42

Publisher

AMER CHEMICAL SOC
DOI: 10.1021/acsanm.0c01998

Keywords

nanotechnology; carbon nanotubes; nitric oxide; platform design; extracellular signaling factor detection

Funding

  1. NIH COBRE grant [P30 GM127200]
  2. National Science Foundation EPSCoR [OIA-1557417]

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This work develops a platform for the immobilization of SWNT sensors with increased fluorescence yield, longevity, fluorescence distribution, and fast reaction times.
Single-walled carbon nanotubes (SWNT) are attractive targets for the formation of high-density sensor arrays. Their small size and high reactivity could allow for the spatial and temporal study of extracellular products to a degree which greatly surpasses contemporary sensors. However, current methods of SWNT immobilization produce a low fluorescence yield that requires a combination of high magnification, exposure time, and laser intensity to combat, thus limiting the sensor's applications. In this work, a platform for the immobilization of SWNT sensors with increased fluorescence yield, longevity, fluorescence distribution, and fast reaction times is developed.

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