4.6 Article

Benefits of early ambulation within 24 h after total knee arthroplasty: a multicenter retrospective cohort study in China

Journal

MILITARY MEDICAL RESEARCH
Volume 8, Issue 1, Pages -

Publisher

BMC
DOI: 10.1186/s40779-021-00310-x

Keywords

Total knee arthroplasty; Early ambulation; Length of stay; Costs; Deep venous thrombosis

Funding

  1. National Health and Family Planning Commission of the People's Republic of China (CN) program [201302007]

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Early ambulation within 24 hours after unilateral total knee arthroplasty in a Chinese population is associated with reduced length of stay, improved knee function, lower hospitalization costs, and lower incidence of deep venous thrombosis and pulmonary infection.
Background Postoperative care has been evolving since the concept of enhanced recovery after surgery (ERAS) was introduced in China. This study aimed to evaluate the effects of early ambulation within 24 h after unilateral total knee arthroplasty (TKA) on postoperative rehabilitation and costs in a Chinese population. Methods This cohort study of patients with knee osteoarthritis who had undergone TKA at 24 large teaching hospitals between January 2014 and November 2016 involved 2687 patients who began ambulating within 24 h (Group A) and 3761 who began ambulating later than 24 h (Group B). The outcome measurements, such as length of stay (LOS), total hospitalization costs, dynamic pain level, knee flexion range of motion (ROM), results of the 12-Item Short Form Survey (SF-12), incidence of thromboembolic events and other complications, were recorded and compared. Results The early ambulation group (Group A) had a shorter LOS and lower hospitalization costs and pain levels than the late ambulation group (Group B). There was a favorable effect in enhancing ROM for patients in Group A compared with patients in Group B. In Group A, patients had significantly higher postoperative SF-12 scores than those in Group B. The incidence of deep venous thrombosis (DVT) and pulmonary infection was significantly lower in Group A than in Group B. The incidence of pulmonary embolism (PE) and other complications did not differ between the two groups. Conclusion Early ambulation within 24 h after TKA was associated with reduced LOS, improved knee function, lower hospitalization costs and lower incidence of DVT and pulmonary infection in the Chinese population.

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