Journal
CHEMICAL COMMUNICATIONS
Volume 57, Issue 34, Pages 4158-4161Publisher
ROYAL SOC CHEMISTRY
DOI: 10.1039/d1cc00987g
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Funding
- National Nature Science Foundation of China [21877084, 21671150, 81171646, 31170776, 21472139, 82003283]
- Science and Technology Commission of Shanghai Municipality [14DZ2261100]
- Fundamental Research Funds for the Central Universities [kx0150720173382]
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A multi-functional nanoplatform (PDA-DTC/Cu-MnO2) was developed for MR imaging-guided multi-therapy (CDT, PTT, and chemotherapy) in cancer treatment. Both in vitro and in vivo results confirmed the biocompatible nanoplatform's ability to significantly induce tumor cell death and inhibit tumor growth.
Herein, a multi-functional nanoplatform (PDA-DTC/Cu-MnO2) was established, which has been employed for MR imaging-guided multi-therapy (CDT, PTT and chemotherapy) for cancer treatment. The in vitro and in vivo results confirmed that the biocompatible nanoplatform could significantly induce tumor cell death and inhibit tumor growth.
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