Defect-engineered porphyrinic metal-organic framework nanoparticles for targeted multimodal cancer phototheranostics†

Defect-engineered porphyrinic MOF nanoparticles were fabricated with an in situ one-pot protocol using cypate as the co-ligand and modulator. This multifunctional nanoplatform integrated the photothermal and multimodal imaging properties of cypate with the photodynamic effects of porphyrins, thus achieving targeted multimodal cancer phototheranostics after folic acid modification.

Automated summary

This study fabricated defect-engineered porphyrinic MOF nanoparticles using cypate as a co-ligand and modulator, integrating the photothermal and multimodal imaging properties of cypate with the photodynamic effects of porphyrins to achieve targeted multimodal cancer phototheranostics.