All in One Epoxy-Based Microfluidic Chips at Your Fingertips

The choice of materials used in the chip fabrication is crucial in microfluidics. They are selected and adapted depending on the available production techniques and associated processes, the involved characterization and measurement methods, the physical and chemical experimental conditions, and the cost. Here, we propose a versatile approach using a combination of epoxy materials to fabricate manually resealable and reusable (>40 times) microfluidic chips which demonstrate numerous potentialities: good chemical resistance, optical (visible and X-ray) transparency, biocompatibility, capability to undergo in average 2.9 bar of liquid pressure, or integration of high aspect ratio (>1500) channels. It thus represents a promising alternative for prototyping in a large panel of applications and fundamental studies.

Automated summary

The choice of materials in chip fabrication for microfluidics is crucial, and this study proposes a versatile approach using a combination of epoxy materials to fabricate microfluidic chips with various potentialities. The chips demonstrate good chemical resistance, optical transparency, biocompatibility, high pressure capability, and integration of high aspect ratio channels, making them promising for prototyping in a wide range of applications and fundamental studies.