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A. Tagde et al.
BLOOD CANCER JOURNAL (2014)
Improving Conventional Enhanced Permeability and Retention (EPR) Effects; What Is the Appropriate Target?
Hisataka Kobayashi et al.
THERANOSTICS (2014)
Reversal of multidrug resistance by stimuli-responsive drug delivery systems for therapy of tumor
Qi Yin et al.
ADVANCED DRUG DELIVERY REVIEWS (2013)
The Cystine/Glutamate Antiporter System xc- in Health and Disease: From Molecular Mechanisms to Novel Therapeutic Opportunities
Jan Lewerenz et al.
ANTIOXIDANTS & REDOX SIGNALING (2013)
β-Phenylethyl isothiocyanate reverses platinum resistance by a GSH-dependent mechanism in cancer cells with epithelial-mesenchymal transition phenotype
Wen-jing Wu et al.
BIOCHEMICAL PHARMACOLOGY (2013)
Glutathione synthesis
Shelly C. Lu
BIOCHIMICA ET BIOPHYSICA ACTA-GENERAL SUBJECTS (2013)
Carrier-free functionalized multidrug nanorods for synergistic cancer therapy
Mengjiao Zhou et al.
BIOMATERIALS (2013)
Oncology Meets Immunology: The Cancer-Immunity Cycle
Daniel S. Chen et al.
IMMUNITY (2013)
Strategies for advancing cancer nanomedicine
Vikash P. Chauhan et al.
NATURE MATERIALS (2013)
Modulation of oxidative stress as an anticancer strategy
Chiara Gorrini et al.
NATURE REVIEWS DRUG DISCOVERY (2013)
Role of Glutathione in Cancer Progression and Chemoresistance
Nicola Traverso et al.
OXIDATIVE MEDICINE AND CELLULAR LONGEVITY (2013)
Autophagy and chemotherapy resistance: a promising therapeutic target for cancer treatment
X. Sui et al.
CELL DEATH & DISEASE (2013)
Beyond oxidative stress: an immunologist's guide to reactive oxygen species
Carl Nathan et al.
NATURE REVIEWS IMMUNOLOGY (2013)
The oxidative stress-inducible cystine/glutamate antiporter, system xc-: cystine supplier and beyond
Marcus Conrad et al.
AMINO ACIDS (2012)
Glutathione levels in human tumors
Michael P. Gamcsik et al.
BIOMARKERS (2012)
Ferroptosis: An Iron-Dependent Form of Nonapoptotic Cell Death
Scott J. Dixon et al.
CELL (2012)
Differential induction of apoptosis in human breast cancer cell lines by phenethyl isothiocyanate, a glutathione depleting agent
Sharifah S. Syed Alwi et al.
CELL STRESS & CHAPERONES (2012)
Macromolecular therapeutics in cancer treatment: The EPR effect and beyond
Hiroshi Maeda
JOURNAL OF CONTROLLED RELEASE (2012)
Aminoferrocene-Based Prodrugs Activated by Reactive Oxygen Species
Helen Hagen et al.
JOURNAL OF MEDICINAL CHEMISTRY (2012)
Inhibition of Mitochondrial Respiration and Rapid Depletion of Mitochondrial Glutathione by β-Phenethyl Isothiocyanate: Mechanisms for Anti-Leukemia Activity
Gang Chen et al.
ANTIOXIDANTS & REDOX SIGNALING (2011)
Hepatic transcriptome and proteome responses against diethyl maleate-induced glutathione depletion in the rat
Shusuke Yamauchi et al.
ARCHIVES OF TOXICOLOGY (2011)
Inhibition of fatty acid oxidation by etomoxir impairs NADPH production and increases reactive oxygen species resulting in ATP depletion and cell death in human glioblastoma cells
Lisa S. Pike et al.
BIOCHIMICA ET BIOPHYSICA ACTA-BIOENERGETICS (2011)
Photodynamic Therapy of Cancer: An Update
Patrizia Agostinis et al.
CA-A CANCER JOURNAL FOR CLINICIANS (2011)
CD44 Variant Regulates Redox Status in Cancer Cells by Stabilizing the xCT Subunit of System xc- and Thereby Promotes Tumor Growth
Takatsugu Ishimoto et al.
CANCER CELL (2011)
Photoactivation switch from type II to type I reactions by electron-rich micelles for improved photodynamic therapy of cancer cells under hypoxia
Huiying Ding et al.
JOURNAL OF CONTROLLED RELEASE (2011)
Starvation Induced Cell Death in Autophagy-Defective Yeast Mutants Is Caused by Mitochondria Dysfunction
Sho W. Suzuki et al.
PLOS ONE (2011)
Oxidative stress mediated apoptosis induced by nickel ferrite nanoparticles in cultured A549 cells
Maqusood Ahamed et al.
TOXICOLOGY (2011)
Effect of gold nanoparticles on glutathione depletion-induced hydrogen peroxide generation and apoptosis in HL7702 cells
Wen Gao et al.
TOXICOLOGY LETTERS (2011)
Silver nanoparticles induce oxidative cell damage in human liver cells through inhibition of reduced glutathione and induction of mitochondria-involved apoptosis
Mei Jing Piao et al.
TOXICOLOGY LETTERS (2011)
Preclinical evaluation of azathioprine plus buthionine sulfoximine in the treatment of human hepatocarcinoma and colon carcinoma
Borja Hernandez-Breijo et al.
WORLD JOURNAL OF GASTROENTEROLOGY (2011)
Isothiocyanates induce oxidative stress and suppress the metastasis potential of human non-small cell lung cancer cells
Xiang Wu et al.
BMC CANCER (2010)
The relationship between cisplatin-induced reactive oxygen species, glutathione, and BCL-2 and resistance to cisplatin
Anamaria Brozovic et al.
CRITICAL REVIEWS IN TOXICOLOGY (2010)
Regulatory T Cells Interfere with Glutathione Metabolism in Dendritic Cells and T Cells
Zhonghua Yan et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2010)
Prodrugs Forming High Drug Loading Multifunctional Nanocapsules for Intracellular Cancer Drug Delivery
Youqing Shen et al.
JOURNAL OF THE AMERICAN CHEMICAL SOCIETY (2010)
Targeting mitochondria for cancer therapy
Simone Fulda et al.
NATURE REVIEWS DRUG DISCOVERY (2010)
Gallic acid-induced lung cancer cell death is related to glutathione depletion as well as reactive oxygen species increase
Bo Ra You et al.
TOXICOLOGY IN VITRO (2010)
Combination therapy: Opportunities and challenges for polymer-drug conjugates as anticancer nanomedicines
Francesca Greco et al.
ADVANCED DRUG DELIVERY REVIEWS (2009)
Reduction-sensitive polymers and bioconjugates for biomedical applications
Fenghua Meng et al.
BIOMATERIALS (2009)
Glutathione: Overview of its protective roles, measurement, and biosynthesis
Henry Jay Forman et al.
MOLECULAR ASPECTS OF MEDICINE (2009)
Association of reactive oxygen species levels and radioresistance in cancer stem cells
Maximilian Diehn et al.
NATURE (2009)
Cu(I)-glutathione complex:: A potential source of superoxide radicals generation
Hernan Speisky et al.
BIOORGANIC & MEDICINAL CHEMISTRY (2008)
Platinum-based chemotherapy plus cetuximab in head and neck cancer
Jan B. Vermorken et al.
NEW ENGLAND JOURNAL OF MEDICINE (2008)
Reactive oxygen species contribute to cell killing and P-glycoprotein downregulation by salvicine in multidrug resistant K562/A02 cells
Yujun Cai et al.
CANCER BIOLOGY & THERAPY (2007)
The resurgence of platinum-based cancer chemotherapy
Lloyd Kelland
NATURE REVIEWS CANCER (2007)
Chemical insights in the concept of hybrid drugs: The antitumor effect of nitric oxide-donating aspirin involves a quinone methide but not nitric oxide nor aspirin
Niels Hulsman et al.
JOURNAL OF MEDICINAL CHEMISTRY (2007)
Cystine/glutamate exchange modulates glutathione supply for neuroprotection from oxidative stress and cell proliferation
Andy Y. Shih et al.
JOURNAL OF NEUROSCIENCE (2006)
The evolution of iron chelators for the treatment of iron overload disease and cancer
DS Kalinowski et al.
PHARMACOLOGICAL REVIEWS (2005)
N-(2-hydroxypropyl)methaerylamide copolymers of a glutathione (GSH)-activated glyoxalase I inhibitor and DNA alkylating agent:: Synthesis, reaction kinetics with GSH, and in vitro antitumor activities
ZB Zheng et al.
BIOCONJUGATE CHEMISTRY (2005)
Cancer immunotherapy: moving beyond current vaccines
SA Rosenberg et al.
NATURE MEDICINE (2004)
Sonodynamic therapy - a review of the synergistic effects of drugs and ultrasound
I Rosenthal et al.
ULTRASONICS SONOCHEMISTRY (2004)
Nonoparticles of biodegradable polymers for new-concept chemotherapy
SS Feng
EXPERT REVIEW OF MEDICAL DEVICES (2004)
Effective treatment of advanced solid tumors by the combination of arsenic trioxide and L-buthionine-sulfoximine
H Maeda et al.
CELL DEATH AND DIFFERENTIATION (2004)
The role of glutathione in cancer
GK Balendiran et al.
CELL BIOCHEMISTRY AND FUNCTION (2004)
The role of glutathione-S-transferase in anti-cancer drug resistance
DM Townsend et al.
ONCOGENE (2003)
Cisplatin: mode of cytotoxic action and molecular basis of resistance
ZH Siddik
ONCOGENE (2003)
Photodynamic therapy with photofrin in combination with Buthionine Sulfoximine (BSO) of human glioma in the nude rat
F Jiang et al.
LASERS IN MEDICAL SCIENCE (2003)
Role of cystine transport in intracellular glutathione level and cisplatin resistance in human ovarian cancer cell lines
S Okuno et al.
BRITISH JOURNAL OF CANCER (2003)
A critical overview of the chemistry of copper-dependent low density lipoprotein oxidation:: Roles of lipid hydroperoxides, α-tocopherol, thiols, and ceruloplasmin
MJ Burkitt
ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS (2001)
tert-Butyl hydroperoxide-induced lipid signaling in hepatocytes:: involvement of glutathione and free radicals
C Martín et al.
BIOCHEMICAL PHARMACOLOGY (2001)
Molecular mechanism of rapid cellular accumulation of anticarcinogenic isothiocyanates
YS Zhang
CARCINOGENESIS (2001)
Role of glutathione in the accumulation of anticarcinogenic isothiocyanates and their glutathione conjugates by murine hepatoma cells
YS Zhang
CARCINOGENESIS (2000)
Combined effect of tumor necrosis factor-related apoptosis-inducing ligand and ionizing radiation in breast cancer therapy
AM Chinnaiyan et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2000)