4.2 Article

Cardiovascular Manifestations of COVID-19 with Special Reference to their Treatment

Journal

LATIN AMERICAN JOURNAL OF PHARMACY
Volume 40, Issue SI, Pages 1-9

Publisher

COLEGIO FARMACEUTICOS PROVINCIA DE BUENOS AIRES

Keywords

angiotensin-converting enzyme 2; antithrombotic agents; cardiovascular disease; COVID-19

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COVID-19, caused by SARS-CoV-2, has global consequences not only in terms of respiratory health but also in significantly impacting the cardiovascular system, leading to conditions such as acute myocarditis, myocardial infarction, arrhythmias, and thrombosis.
Coronavirus disease 2019 (COVID-19) represented as a global pandemic which mainly happened due to severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), viral affected huge numbers of individuals all around the world. Besides the viral morbidity and mortality, the economy and health care system have also been significantly strained due to high viral transmission. COVID-19 virus is known as a virus of pneumonia which causes acute respiratory distress syndrome (ARDS) and may be alife threatening. There was evidence supposed that the virus affected the cardiovascular system significantly via its direct damage to the myocardium, acute systemic inflammatory restraint, hypoxia, a right strain of the heart due to acute respiratory distress syndrome and injury of the lung, also rupture of the plaque due to inflammation. Essential cardiac manifestations showed acute myocarditis, myocardial infarction, arrhythmia, and showed thrombosis. Many accepted documents have been done that support the management of cardiovascular disease due to the COVID-19 pandemic. The aim of this review study is to explain the cardiovascular system damage caused by SARS-CoV-2 with precise comprehensions for the underlying mechanisms to create a liable management approach for these patients.

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