Journal
CHEMICAL COMMUNICATIONS
Volume 57, Issue 22, Pages 2776-2779Publisher
ROYAL SOC CHEMISTRY
DOI: 10.1039/d1cc00145k
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Funding
- National Natural Science Foundation of China [21778013, 22077024, U20A200458]
- Natural Science Foundation of Hebei Province [B2020201092]
- Foundation of the Department of Science and Technology of Hebei Province [19241303D]
- Priority Strategy Project of Key Laboratory of Medicinal Chemistry and Molecular Diagnosis of Ministry of Education [ts2019002]
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A mannose-modified perylene monoimide derivative PMI-Man has been developed, which exhibits highly selective binding to double-stranded DNA molecules, potent live/dead cell imaging, and histological imaging via both confocal and light microscopies. This approach may be utilized to create a universal colorful staining method for human tissues suitable for both confocal and light microscopies.
A mannose-modified perylene monoimide derivative PMI-Man was developed, which shows highly selective binding to double-stranded DNA molecules, potent live/dead cell imaging, and histological imaging via both confocal and light microscopies. This approach can be used to develop a universal colorful staining method for human tissues for both confocal and light microscopies.
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