4.6 Article

A green metal-free one-pot microwave assisted synthesis of 1,4-dihydrochromene triazoles

Journal

RSC ADVANCES
Volume 11, Issue 17, Pages 10336-10339

Publisher

ROYAL SOC CHEMISTRY
DOI: 10.1039/d1ra01169c

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Funding

  1. FAPESP [2014/50249-8, 2020/10246-0, 2020/01255-6]
  2. GlaxoSmithKline
  3. CAPES [001]
  4. PNPD/CAPES
  5. CNPq

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This study successfully synthesized several 4-aryl-1,4-dihydrochromene-triazoles via a metal-free one-pot procedure using PEG400 as the sole solvent in an eco-friendly process. The triazole derivatives were obtained in good yields and short reaction times with microwave irradiation starting from readily accessible building blocks.
The synthesis of several 4-aryl-1,4-dihydrochromene-triazoles was achieved via a metal-free one-pot procedure using PEG400 as the sole solvent in an eco-friendly process. Using microwave irradiation, the triazole derivatives were obtained in good yields and short reaction times starting from readily accessible building blocks.

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