An electrochemical perspective on the roles of ligands in the merger of transition-metal catalysis and electrochemistry

The merger of transition-metal catalysis and electrochemistry has emerged as a very versatile and robust synthetic tool in organic synthesis. Like in their non-electrochemical variants, ligands also play crucial roles in fundamental reactions in transition-metal catalysis under electrochemical conditions. Herein, a perspective on the roles of ligands in transition-metal catalysis under electrochemical conditions is provided with selected transformations enabled by such a merger including C-H functionalization, difunctionalization of alkenes, cross-coupling reactions and carboxylation with CO2.

Automated summary

The merger of transition-metal catalysis and electrochemistry is a versatile and powerful synthetic tool in organic synthesis, where ligands play crucial roles in fundamental reactions under these combined conditions. Selected transformations enabled by this merger include C-H functionalization, difunctionalization of alkenes, cross-coupling reactions, and carboxylation with CO2.