4.4 Review

Bioactive Polymeric Materials for the Advancement of Regenerative Medicine

Journal

JOURNAL OF FUNCTIONAL BIOMATERIALS
Volume 12, Issue 1, Pages -

Publisher

MDPI
DOI: 10.3390/jfb12010014

Keywords

biopolymers; polymer modification; bioactivity; regenerative medicine; tissue regeneration

Funding

  1. Tagliatela College of Engineering
  2. Biomedical Engineering program
  3. Biomaterials and Medical Device Innovation laboratory
  4. Wang Laboratory at the University of New Haven

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This article discusses the importance of biopolymers in regenerative medicine and explores the research on their composition and function relationships. It also outlines the current applications of biopolymers under study and the prospects for modifying them for multibioactivity.
Biopolymers are widely accepted natural materials in regenerative medicine, and further development of their bioactivities and discoveries on their composition/function relationships could greatly advance the field. However, a concise insight on commonly investigated biopolymers, their current applications and outlook of their modifications for multibioactivity are scarce. This review bridges this gap for professionals and especially freshmen in the field who are also interested in modification methods not yet in commercial use. A series of polymeric materials in research and development uses are presented as well as challenges that limit their efficacy in tissue regeneration are discussed. Finally, their roles in the regeneration of select tissues including the skin, bone, cartilage, and tendon are highlighted along with modifiable biopolymer moieties for different bioactivities.

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