Journal
FORENSIC SCIENCE INTERNATIONAL
Volume 272, Issue -, Pages E1-E6Publisher
ELSEVIER IRELAND LTD
DOI: 10.1016/j.forsciint.2017.01.006
Keywords
mRNA profiling; Body fluid identification; Aged bloodstains
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Funding
- Technical Research Fund of China's Ministry of Public Security [2015JSYJA02]
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Remarkable progress has been made in recent years on the research of body fluid identification through messenger RNA(mRNA) profiling. In order to examine the viability of mRNA profiling as a method to identify aged bloodstains, this study tested two groups of bloodstain samples, dated 30 years and 50 years back respectively, on seven blood specific markers, i.e. HBB, HBA, GYPA, CD93, ALAS2, SPTB (91 bp and 247 bp primers), and PBGD. Test results indicate that HBA and HBB are the most stable markers in aged bloodstains, returning positive results in over 80% of the 50-year-old samples and over 90% of the 30-year- old samples. This finding proves mRNA profiling an effective way of identifying aged bloodstains. (C) 2017 Elsevier Ireland Ltd. All rights reserved.
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