4.6 Article

An organophosphorus-mediated cross-Rauhut-Currier/Wittig domino reaction for the efficient synthesis of trisubstituted cyclopentenes

Journal

ORGANIC & BIOMOLECULAR CHEMISTRY
Volume 19, Issue 11, Pages 2487-2491

Publisher

ROYAL SOC CHEMISTRY
DOI: 10.1039/d1ob00150g

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Funding

  1. National Natural Science Foundation of China [21372195]

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An efficient organophosphorus-mediated cross-Rauhut-Currier/Wittig domino reaction has been developed for the synthesis of trisubstituted cyclopentenes, showing advantages of mild reaction conditions, high efficiency, environmental friendliness, and satisfactory yields.
An efficient organophosphorus-mediated cross-Rauhut-Currier/Wittig domino reaction of vinyl ketones with chalcones has been developed for the synthesis of trisubstituted cyclopentenes. The new synthetic method has the advantages of mild reaction conditions, high efficiency, environmental friendliness and satisfactory yields.

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