Journal
WORLD JOURNAL OF EMERGENCY MEDICINE
Volume 12, Issue 1, Pages 48-53Publisher
ZHEJIANG UNIV PRESS
DOI: 10.5847/wjem.j.1920-8642.2021.01.008
Keywords
Transcatheter aortic valve implantation; Balloon aortic valvuloplasty; Balloon size; Permanent pacemaker implantation
Categories
Funding
- National Key RD Plan [2017YFC1104202]
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This study found that performing small balloon aortic valvuloplasty (BAV) after transcatheter aortic valve implantation (TAVI) can reduce the need for permanent pacemaker implantation (PPMI). The rate of PPMI was significantly lower in the small BAV group compared to the normal BAV group, and small BAV, the ratio of prosthesis diameter to annulus diameter, and mean aortic gradient by echo in the basement were identified as independent predictors of PPMI.
BACKGROUND: This study aims to investigate whether small balloon aortic valvuloplasty (BAV) reduces the need for permanent pacemaker implantation (PPMI) after transcatheter aortic valve implantation (TAVI). METHODS: This was a retrospective analysis using data from our local TAVI database. Small BAV was defined as a small balloon size (= 18 mm) pre-dilatation. Normal BAV was defined as a balloon size >18 mm. The primary endpoint was the incidence of new PPMI. RESULTS: Of 99 consecutive TAVI patients, five patients were excluded due to pre-existing permanent pacemaker. Patients in the small BAV group (n=57) had a significantly lower PPMI rate compared with the normal BAV group (n=37) (3.5% vs. 18.9%, P=0.026). Moderate or severe aortic valve regurgitation post-procedure was similar between the small BAV and normal BAV groups (5.3% vs. 8.1%, P=0.480); likewise, the mean aortic gradient post-procedure did not differ significantly (11.5 +/- 5.2 mmHg vs. 12.2 +/- 7.3 mmHg, 1 mmHg=0.133 kPa, P=0.580) between the groups. Device success rates were also similar (94.7% vs. 91.8%, P=0.680). In multivariable analysis, small BAV (P=0.027), the ratio of prosthesis diameter to annulus diameter (P=0.048), and mean aortic gradient by echo in the basement (P=0.021) were independent predictors of PPMI. CONCLUSIONS: The small BAV strategy is associated with a low rate of permanent pacemaker implantation after transcatheter self-expanding valve implantation in this single-center observational study.
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