Journal
CHEMICAL COMMUNICATIONS
Volume 57, Issue 21, Pages 2629-2632Publisher
ROYAL SOC CHEMISTRY
DOI: 10.1039/d0cc08089f
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Funding
- Science and Technology Cooperation Project between the Chinese and Australian Governments [2017YFE0132300]
- Natural Science Foundation of Jiangsu Province [BK20201184]
- Science and Technology Project of Ji Hua Laboratory [X190191TD190]
- China Postdoctoral Science Foundation [2020M672542]
- Guangdong Basic and Applied Basic Research Foundation [2019A1515110877]
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The work has developed a simple and reliable platform for simultaneous analysis of telomerase and miRNA using a three-dimensional bipedal DNA walking strategy. With the advantages of fast, sensitive and selective analysis, the method has great potential for early clinical diagnosis applications.
In this work, we have developed a simple and reliable platform for simultaneous analysis of telomerase and miRNA. A three-dimensional bipedal DNA walking strategy is designed utilizing gold nanoparticles and MnO2 nanosheets. Given the merits of fast, sensitive and selective analysis, the developed method has great potential application in early clinical diagnosis.
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