Journal
MEMORIAS DO INSTITUTO OSWALDO CRUZ
Volume 116, Issue -, Pages -Publisher
FUNDACO OSWALDO CRUZ
DOI: 10.1590/0074-02760200634
Keywords
Leishmania; Trypanosoma cruzi; genomics; transcriptomics; functional genomics
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The availability of Trypanosomatid genomic data in public databases has led to numerous experimental possibilities, contributing to a more comprehensive understanding of the biology of these parasites and their interactions with hosts.
The availability of Trypanosomatid genomic data in public databases has opened myriad experimental possibilities that have contributed to a more comprehensive understanding of the biology of these parasites and their interactions with hosts. In this review, after brief remarks on the history of the Trypanosoma cruzi and Leishmania genome initiatives, we present an overview of the relevant contributions of genomics, transcriptomics and functional genomics, discussing the primary obstacles, challenges, relevant achievements and future perspectives of these technologies.
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