4.7 Article

Accelerated DNA tetrahedron-based molecular beacon for efficient microRNA imaging in living cells

Journal

CHEMICAL COMMUNICATIONS
Volume 57, Issue 26, Pages 3251-3254

Publisher

ROYAL SOC CHEMISTRY
DOI: 10.1039/d0cc08172h

Keywords

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Funding

  1. National Key R&D Program of China [2018YFA0902600]
  2. National Natural Science Foundation of China [11674185, 11947016, 21775025, U1705281]
  3. Natural Science Foundation of Fujian [2019J01764, 2019J05110, 2020J01861]
  4. Fuzhou science and technology project [2020-S-28, 2020-S-29]

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In this study, an accelerated DNA tetrahedron based molecular beacon was developed for efficient detection and imaging of miRNA in living cells. The research provides an improved strategy for fluorescence amplified RNA imaging in early clinical diagnosis.
Herein, we develop an accelerated DNA tetrahedron based molecular beacon for efficient detection and imaging of miRNA in living cells. Our study provides an improved strategy for fluorescence amplified RNA imaging in early clinical diagnosis.

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