4.6 Review

Recent advances in the synthesis of pyrido[1,2-a]indoles

Journal

ORGANIC & BIOMOLECULAR CHEMISTRY
Volume 19, Issue 16, Pages 3509-3526

Publisher

ROYAL SOC CHEMISTRY
DOI: 10.1039/d1ob00153a

Keywords

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Funding

  1. CNRS
  2. Universite Paris-Saclay
  3. CSC (Chinese Scholarship Council)

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Research on new synthetic pathways to access the pyrido[1,2-a]indole unit found in various organic compounds has intensified in recent years. This review categorizes the synthesis of pyrido[1,2-a]indoles into two parts, based on whether metal catalysis is used or not.
The pyrido[1,2-a]indole unit found in many organic compounds such as natural products, pharmaceuticals, and materials, has intensively stimulated the research of new synthetic pathways giving access to this heterocyclic nucleus in very recent years. In this review, the synthesis of pyrido[1,2-a]indoles will be divided into two parts, which concern accesses to this skeleton using or not metal catalysis.

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