Regioselective intramolecular sp2 C-H amination: direct vs. mediated electrooxidation

We reported an electrochemical intramolecular C-H amination approach to construct benzimidazole-fused phenanthridines. This electrochemical approach was compatible with a variety of functional groups, including ester, silyl, thioether, pyridyl and amine groups. With the triarylamine-mediated and direct oxidation strategies, the intramolecular C-H amination proceeds with high regioselectivities under oxidant- and metal-free conditions. Moreover, this protocol provided an alternative approach to access organic luminophores.

Automated summary

An electrochemical intramolecular C-H amination approach was developed to construct benzimidazole-fused phenanthridines. This method is compatible with a variety of functional groups and can achieve high regioselectivities under oxidant- and metal-free conditions. It provides an alternative pathway for accessing organic luminophores.