Journal
FOOD CHEMISTRY
Volume 235, Issue -, Pages 227-233Publisher
ELSEVIER SCI LTD
DOI: 10.1016/j.foodchem.2017.05.034
Keywords
Camellia var. assamica; Flavanone; YingDe black tea; alpha-Glucosidase inhibitory activity
Funding
- National Natural Science Foundation of China [31671957, 31101323]
- Jinan University
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YingDe black tea is produced from crude tea prepared from leaves of Camellia sinensis var. assamica. In this work, we isolated and identified five novel flavanones, namely, amelliaone A-E (1-5), along with seven known compounds 6-12 from the ethanol extract of YingDe black tea. The structures of these five novel phenolic compounds were determined using extensive 1D and 2D nuclear magnetic resonance spectroscopy experiments. The compounds were further evaluated for antioxidant, alpha-glucosidase inhibitory, and cytotoxic activities. Compound I exhibited higher alpha-glucosidase inhibitory activity with a half maximum inhibitory concentration value (IC50) of 10.2 mu M compared with acarbose (18.2 mu M). (C) 2017 Elsevier Ltd. All rights reserved.
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