Journal
BIOMATERIALS SCIENCE
Volume 9, Issue 5, Pages 1574-1582Publisher
ROYAL SOC CHEMISTRY
DOI: 10.1039/d0bm01269f
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Surface acoustic waves (SAW) are sound waves traveling on the surface of an elastic material, offering robust control of acoustic energy and versatility. Integration of SAW with modern lab-on-a-chip technology has found numerous applications in micro/nanosystems, particularly in the field of biomaterials where SAW technology provides exceptional opportunities for research and manipulation at small scales.
A surface acoustic wave (SAW) is a sound wave travelling on the surface of an elastic material. SAW offers a robust control of the acoustic energy leading to an unparalleled versatility. As an actuator, SAW can exert acoustic forces on particles and fluids thus enabling dexterous micro/nanoscale manipulations. As a sensor, SAW has a unique sensing capability upon changes in the environment. On-chip SAW technology, in which SAW is integrated with modern lab-on-a-chip (LOC), has drawn a lot of attention in recent years and found various exciting applications in micro/nanosystems. In particular, its well-known biocompatibility provides on-chip SAW technology as an exceptional platform for biomaterials research at the small-scale. In this minireview, we highlighted recent advances of on-chip SAW technology for biomaterials manipulation and characterization with a focus on cell-based (e.g. single-cell and multicellular) biomaterials. We also discussed and shared our perspective on future directions for this emerging research field.
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