Journal
BMJ OPEN
Volume 11, Issue 5, Pages -Publisher
BMJ PUBLISHING GROUP
DOI: 10.1136/bmjopen-2021-049872
Keywords
general medicine (see internal medicine); quality in health care; public health; qualitative research
Categories
Funding
- National Research Programme 'Smarter Health Care' (NRP74) by the Swiss National Science Foundation [407440_167193]
- University of Zurich
- University Hospital Zurich
- Swiss National Science Foundation (SNF) [407440_167193] Funding Source: Swiss National Science Foundation (SNF)
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The study implemented a cluster randomised controlled trial to test the effectiveness of a medication review and communication stimulus between hospital physicians and general practitioners on rehospitalisation of multimorbid older patients. Results showed successful recruitment of hospitals, high intervention dose but limited fidelity, and challenges in patient recruitment and retention.
Objectives To study the implementation of a cluster randomised controlled effectiveness-implementation hybrid trial testing the effectiveness of a medication review at hospital discharge combined with a communication stimulus between hospital physicians (HPs) and general practitioners (GPs) on rehospitalisation of multimorbid older patients. Design Extension of Grant's mixed method process evaluation framework to trials with multilevel clustering. Setting General internal medicine wards in Swiss hospitals. Participants Convenience samples of 15 chief physicians (of 21 hospitals participating in the effectiveness trial), 60 (74) senior HPs, 65 (164) junior HPs and 187 (411) GPs. Implementation strategy Two-hour teaching sessions for senior HPs on a patient-centred, checklist-guided discharge routine. Process evaluation components Data collection on recruitment, delivery and response from chief physicians (semistructured interviews), senior HPs, junior HPs, GPs (surveys) and patients (via HPs). Quantitative data were summarised using descriptive statistics, and interviews analysed using thematic analysis. Outcome measures Intervention dose (quantitative), implementation fidelity (qualitative), feasibility and acceptability, facilitators and barriers, implementation support strategies. Results Recruitment of hospitals was laborious but successful, with 21 hospitals recruited. Minimal workload and a perceived benefit for the clinic were crucial factors for participation. Intervention dose was high (95% of checklist activities carried out), but intervention fidelity was limited (discharge letters) or unknown (medication review). Recruitment and retention of patients was challenging, partly due to patient characteristics (old, frail) and the COVID-19 pandemic: Only 612 of the anticipated 2100 patients were recruited, and 31% were lost to follow-up within the first month after discharge. The intervention was deemed feasible and helpful by HPs, and the relevance of the topic appreciated by both HPs and GPs. Conclusions The results from this evaluation will support interpretation of the findings of the effectiveness study and may inform researchers and policy makers who aim at improving hospital discharge.
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