4.7 Article

Gold nanoparticle integrated artificial nanochannels for label-free detection of peroxynitrite

Journal

CHEMICAL COMMUNICATIONS
Volume 57, Issue 29, Pages 3583-3586

Publisher

ROYAL SOC CHEMISTRY
DOI: 10.1039/d0cc08410g

Keywords

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Funding

  1. National Natural Science Foundation of China [21904031, 21625503]
  2. Natural Science Foundation of Hubei Province [2019CFB121]
  3. Application Foundation Frontier Project by Wuhan Science and Technology Bureau [2018060401011320]

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This study introduces a label-free method for rapid and highly sensitive detection of peroxynitrite using well-designed artificial nanochannels integrated with gold nanoparticles, paving a new pathway for developing a versatile platform for detecting various biological small molecules and reactive species.
A label-free method for rapid and highly sensitive detection of peroxynitrite (ONOO-) was proposed by employing well-designed N-(4-aminobutyl)-N-ethylisoluminol (ABEI) capped AuNP integrated artificial nanochannels. This work paves a new pathway to develop a versatile platform for the detection of different biological small molecules and reactive species.

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