4.7 Article

A near-infrared fluorescent probe for accurately diagnosing cancer by sequential detection of cysteine and H+

Journal

CHEMICAL COMMUNICATIONS
Volume 57, Issue 39, Pages 4811-4814

Publisher

ROYAL SOC CHEMISTRY
DOI: 10.1039/d1cc01228b

Keywords

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Funding

  1. National Natural Science Foundation of China [21775133]
  2. Scientific Research Fund of Hunan Provincial Education Department [19A479]
  3. Open Research Fund of School of Chemistry and Chemical Engineering, Henan Normal University [2020YB01]
  4. Key Project of Science and Technology of Henan Province [202102310215]
  5. Degree & Postgraduate Education Reform Project of Hunan Province [2019JGYB113]
  6. Hunan Provincial Innovation Foundation for Postgraduates [CX20190483, XDCX2020B115]

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The near-infrared fluorescent probe CyAc is synthesized for accurate cancer diagnosis by sequential detection of Cys and H+. It can not only distinguish between normal cells and cancer cells, but also between normal and tumor mice.
A near-infrared fluorescent probe, CyAc, is synthesized for accurately diagnosing cancer in vivo by sequential detection of Cys and H+. CyAc can not only achieve a good distinction between normal cells and cancer cells, but also distinguish normal mice from tumor mice.

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