Pluripotent and Multipotent Stem Cells and Current Therapeutic Applications: Review

There is numerous evidence for the presence of stem cells, which is important for the treatment of a wide variety of disease conditions. Stem cells have a great therapeutic effect on different degenerative diseases through the development of specialized cells. Embryonic stem (ES) cells are derived from preimplantation embryos, which have a natural karyotype. This cell has the capacity of proliferation indefinitely and undifferentiated. Stem cells are very crucial for the treatment of different chronic and degenerative diseases. For instance, stem cell clinical trials have been done for ischemic heart disease. Also, the olfactory cells for spinal cord lesions and human fetal pancreatic cells for diabetes mellitus are the other clinical importance of stem cell therapy. Extracellular matrix (ECM) and other environmental factors influence the fate and activity of stem cells.

Automated summary

Stem cells play a crucial role in the treatment of various diseases, with their ability to proliferate indefinitely and remain undifferentiated. Clinical trials have shown their effectiveness in treating conditions such as ischemic heart disease, spinal cord injuries, and diabetes mellitus. The fate and activity of stem cells are influenced by factors such as the extracellular matrix and the cellular environment.