4.7 Article

Nonblinking carbon dots for imaging and tracking receptors on a live cell membrane

Journal

CHEMICAL COMMUNICATIONS
Volume 57, Issue 45, Pages 5554-5557

Publisher

ROYAL SOC CHEMISTRY
DOI: 10.1039/d1cc01120k

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Funding

  1. National Natural Science Foundation of China [21874154, 42061134020]
  2. Fundamental Research Funds for the Central Universities [18CX02126A]
  3. Research Project of Qingdao Customs [QK202035]

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The study introduces a method to develop non-blinking and photoresistant fluorescent carbon dots by introducing multiple aromatic domains onto a single carbon dot, demonstrating their great potential for imaging and tracking receptors on a live cell membrane.
Blinking occurs with nearly all fluorophores including organic dyes, fluorescent proteins, semiconductor quantum dots and carbon dots (CDs). We developed non-blinking and photoresistant fluorescent CDs by introducing multiple aromatic domains onto a single carbon dot and demonstrated their great potential for imaging and tracking of receptors on a live cell membrane.

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