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Multicolor Luminescent Gold Nanoclusters: From Structure to Biosensing and Bioimaging

Journal

PROGRESS IN CHEMISTRY
Volume 33, Issue 2, Pages 179-187

Publisher

CHINESE ACAD SCIENCES
DOI: 10.7536/PC200637

Keywords

gold nanoclusters; luminescence; ligands; biosensing; bioimaging

Funding

  1. National Natural Science Foundation of China [21904011, 21890742]
  2. Fundamental Research Funds for the Central Universities [FRF.TP.19.010A3]
  3. Open Fund of Guangdong Provincial Key Laboratory of Luminescence from Molecular Aggregates(South China University of Technology) [2019B030301003]

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Gold nanoclusters are a new type of nanomaterials with luminescent properties, widely used in fields such as photocatalysis, optical devices, sensing, and imaging. By controlling the number of gold atoms and composition of ligands, different emission bands can be achieved under the same excitation. Research on synthesis methods and factors affecting the luminescent properties of gold nanoclusters, as well as their applications in biosensing and bioimaging, have been discussed in this paper.
Gold nanoclusters are a new kind of Quasi.molecule nanomaterials with luminescent properties. By controlling the number of gold atoms and the composition of ligands. gold nanoclusters can realize the emission of different bands under the same excitation. thus showing the colorful luminescence characteristics. which make them widely used in many fields such as photocatalysis. optical devices. sensing. and imaging. Therefore. the development and optimization of the synthesis method of gold nanoclusters with good fluorescenceperformance have been a research hotspot in the field of chemical biomaterials. In this paper. based on the luminescent color of gold nanoclusters. the synthesis principles and methods of corresponding gold nanoclusters are summarized according to different colors. and the factors affecting the luminescent properties of gold nanoclusters are explored. At the same time. the applications of these colorful gold nanoclusters in biosensing and bioimaging in recent years are summarized. and the challenges and development trends of gold nanoclusters are discussed and prospected respectively.

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