4.1 Article

Efficacy of chemotherapy and palliative hypofractionated radiotherapy for cats with nasal lymphoma

Journal

JOURNAL OF VETERINARY MEDICAL SCIENCE
Volume 83, Issue 3, Pages 456-460

Publisher

JAPAN SOC VET SCI
DOI: 10.1292/jvms.20-0464

Keywords

cat; chemotherapy; nasal lymphoma; prognosis; radiotherapy

Funding

  1. Japan Society for the Promotion of Science, KAKENHI [20H03143, 15K18797]
  2. Grants-in-Aid for Scientific Research [20H03143, 15K18797] Funding Source: KAKEN

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The study indicated that similar efficacy could be achieved by palliative hypofractionated radiotherapy, chemotherapy, or a combination of them for nasal lymphoma in cats, with no significant difference in overall survival and progression free survival among these three treatment groups.
Nasal lymphoma (NL) is the most common nasal tumor in cats, and radiotherapy, chemotherapy, or a combination of these treatments have been described as the treatment for this disease. However, the previous studies included various machines and protocols of radiotherapy. Therefore, we aimed to retrospectively compare the prognosis among cases treated with palliative hypofractionated radiotherapy, chemotherapy, and a combination of them with united machine and protocol of radiotherapy. When compared overall survival and progression free survival, there was no significant difference among these three groups. The data of this study suggested that similar efficacy could be achieved by palliative hypofractionated radiotherapy, chemotherapy, or a combination of them.

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