Journal
CHEMICAL COMMUNICATIONS
Volume 57, Issue 50, Pages 6145-6148Publisher
ROYAL SOC CHEMISTRY
DOI: 10.1039/d1cc01830b
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Funding
- National Natural Science Foundation of China [21927811, 21874086, 21775094]
- National Key R&D Program of China [2019YFA0210100]
- Natural Science Foundation of Shandong Province [ZR2020QB106]
- Youth Innovation Science and Technology Program of Higher Education Institution of Shandong Province [2019KJC022]
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A novel porphyrin-containing covalent organic framework (COF) was synthesized for decorating selenium nanoparticles (Se NPs) via in situ reduction. Selenium nanoparticle-mediated therapy (SeT) was combined with photodynamic therapy (PDT) to enhance anticancer effects and address the limitations of PDT.
A porphyrin-containing covalent organic framework (COF) was synthesized as a substrate for decorating selenium nanoparticles (Se NPs) via in situ reduction. Se NP-mediated therapy (SeT) was carried out in conjunction with photodynamic therapy (PDT) to provide an increased anticancer effect and remedy the constrained efficacy of PDT.
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