Journal
CLINICAL INFECTIOUS DISEASES
Volume 72, Issue 7, Pages E192-E195Publisher
OXFORD UNIV PRESS INC
DOI: 10.1093/cid/ciaa1702
Keywords
COVID-19; pediatrics; seroprevalence; rapid diagnostic test; antibody
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Funding
- Department of Woman, Child and Adolescent Medicine
- Department of Diagnostics, Geneva University Hospitals and Faculty of Medicine, Geneva, Switzerland.
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In a study of 208 children seeking medical care, the seropositivity rate of anti-SARS-CoV-2 IgG antibodies was 8.7%, suggesting a similar infection rate to that of adults but greater than the incidence of RT-PCR-confirmed pediatric cases by over 100-fold. The MEDsan IgG rapid diagnostic test demonstrated accurate performance compared to the gold-standard combined ELISA + immunofluorescence.
In 208 children seeking medical care, the seropositivity rate of anti-SARS-CoV-2 IgG antibodies was 8.7%, suggesting an infection rate similar to that observed in adults but >100-fold the incidence of RT-PCR-confirmed pediatric cases. Compared with the gold-standard combined ELISA + immunofluorescence, the MEDsan IgG rapid diagnostic test performed accurately.
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