Journal
ORGANIC & BIOMOLECULAR CHEMISTRY
Volume 19, Issue 23, Pages 5127-5132Publisher
ROYAL SOC CHEMISTRY
DOI: 10.1039/d1ob00451d
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Funding
- JSPS KAKENHI [JP16K08180, JP18K14876, JP19K06981]
- Nagai Memorial Research Scholarship from Pharmaceutical Society of Japan
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The first total synthesis of corallocin A was achieved with high stereoselectivity and good yield using the Suzuki coupling reaction as a key step. Robust transformations including Vilsmeier-Haack formylation and Wittig reaction were utilized for effective access to corallocin A.
The first total synthesis of corallocin A is described herein. The Suzuki coupling reaction as a key step proceeded with high stereoselectivity and in good yield. Robust transformations, including Vilsmeier-Haack formylation and Wittig reaction, allowed for effective access to corallocin A.
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