Drug targets, mechanisms of drug action, and therapeutics against SARS-CoV-2

The recent outbreak of COVID-19 has affected human lives severely. The human-to-human transmission of this viral disease has become deadly due to the unavailability of COVID-19 specific drugs. Here, an overview of various attempts made to design different therapeutic agents against various structural and non-structural proteins of SARS-CoV-2 has been summarized. Emphasis has been made to highlight the mechanisms of drug action and ways to design better inhibitors of these proteins. The roles of anti-oxidants and vitamins in suppressing COVID19 are also discussed.

Automated summary

This article summarizes various attempts to design therapeutic agents against SARS-CoV-2, highlighting the mechanisms of drug action and ways to design better protein inhibitors. The roles of antioxidants and vitamins in suppressing COVID19 are also discussed.