Related references
Note: Only part of the references are listed.FuzDB: database of fuzzy complexes, a tool to develop stochastic structure-function relationships for protein complexes and higher-order assemblies
Marton Miskei et al.
NUCLEIC ACIDS RESEARCH (2017)
Structural Basis of Ribosomal S6 Kinase 1 (RSK1) Inhibition by S100B Protein: MODULATION OF THE EXTRACELLULAR SIGNAL-REGULATED KINASE (ERK) SIGNALING CASCADE IN A CALCIUM-DEPENDENT WAY
Gergo Gogl et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2016)
The Structure and Dynamics of Higher-Order Assemblies: Amyloids, Signalosomes, and Granules
Hao Wu et al.
CELL (2016)
Structural basis for concerted recruitment and activation of IRF-3 by innate immune adaptor proteins
Baoyu Zhao et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2016)
A Derived Allosteric Switch Underlies the Evolution of Conditional Cooperativity between HOXA11 and FOXO1
Mauris C. Nnamani et al.
CELL REPORTS (2016)
Plasticity of an Ultrafast Interaction between Nucleoporins and Nuclear Transport Receptors
Sigrid Milles et al.
CELL (2015)
Short linear motifs - ex nihilo evolution of protein regulation
Norman E. Davey et al.
CELL COMMUNICATION AND SIGNALING (2015)
Nuclear bodies: the emerging biophysics of nucleoplasmic phases
Lian Zhu et al.
CURRENT OPINION IN CELL BIOLOGY (2015)
Fuzzy complexes: Specific binding without complete folding
Rashmi Sharma et al.
FEBS LETTERS (2015)
Formation and Maturation of Phase-Separated Liquid Droplets by RNA-Binding Proteins
Yuan Lin et al.
MOLECULAR CELL (2015)
Residue-by-Residue View of In Vitro FUS Granules that Bind the C-Terminal Domain of RNA Polymerase II
Kathleen A. Burke et al.
MOLECULAR CELL (2015)
Phase Transition of a Disordered Nuage Protein Generates Environmentally Responsive Membraneless Organelles
Timothy J. Nott et al.
MOLECULAR CELL (2015)
Polymer physics of intracellular phase transitions
Clifford P. Brangwynne et al.
NATURE PHYSICS (2015)
Intrinsically disordered proteins in cellular signalling and regulation
Peter E. Wright et al.
NATURE REVIEWS MOLECULAR CELL BIOLOGY (2015)
An intrinsically disordered region of methyl-CpG binding domain protein 2 (MBD2) recruits the histone deacetylase core of the NuRD complex
Megha A. Desai et al.
NUCLEIC ACIDS RESEARCH (2015)
The disordered P granule protein LAF-1 drives phase separation into droplets with tunable viscosity and dynamics
Shana Elbaum-Garfinkle et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2015)
The Selective Autophagy Receptor p62 Forms a Flexible Filamentous Helical Scaffold
Rodolfo Ciuffa et al.
CELL REPORTS (2015)
Plasticity in PYD assembly revealed by cryo-EM structure of the PYD filament of AIM2
Alvin Lu et al.
CELL DISCOVERY (2015)
Folding of an intrinsically disordered protein by phosphorylation as a regulatory switch
Alaji Bah et al.
NATURE (2015)
Intrinsically Disordered Proteins and Intrinsically Disordered Protein Regions
Christopher J. Oldfield et al.
ANNUAL REVIEW OF BIOCHEMISTRY, VOL 83 (2014)
The proline-rich region of 18.5 kDa myelin basic protein binds to the SH3-domain of Fyn tyrosine kinase with the aid of an upstream segment to form a dynamic complex in vitro
Miguel De Avila et al.
BIOSCIENCE REPORTS (2014)
Prion-like Polymerization Underlies Signal Transduction in Antiviral Immune Defense and Inflammasome Activation
Xin Cai et al.
CELL (2014)
Unified Polymerization Mechanism for the Assembly of ASC-Dependent Inflammasomes
Alvin Lu et al.
CELL (2014)
Classification of Intrinsically Disordered Regions and Proteins
Robin van der Lee et al.
CHEMICAL REVIEWS (2014)
A Million Peptide Motifs for the Molecular Biologist
Peter Tompa et al.
MOLECULAR CELL (2014)
The ensemble nature of allostery
Hesam N. Motlagh et al.
NATURE (2014)
A sequence-specific transcription activator motif and powerful synthetic variants that bind Mediator using a fuzzy protein interface
Linda Warfield et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2014)
Signalosome assembly by domains undergoing dynamic head-to-tail polymerization
Mariann Bienz
TRENDS IN BIOCHEMICAL SCIENCES (2014)
Competitive and Cooperative Interactions Mediate RNA Transfer from Herpesvirus Saimiri ORF57 to the Mammalian Export Adaptor ALYREF
Richard B. Tunnicliffe et al.
PLOS PATHOGENS (2014)
Dual Specificity Kinase DYRK3 Couples Stress Granule Condensation/Dissolution to mTORC1 Signaling
Frank Wippich et al.
CELL (2013)
Higher-Order Assemblies in a New Paradigm of Signal Transduction
Hao Wu
CELL (2013)
Alternative splicing of intrinsically disordered regions and rewiring of protein interactions
Marija Buljan et al.
CURRENT OPINION IN STRUCTURAL BIOLOGY (2013)
Modulation of allostery by protein intrinsic disorder
Allan Chris M. Ferreon et al.
NATURE (2013)
Supertertiary Structure of the MAGUK Core from PSD-95
Jun Zhang et al.
STRUCTURE (2013)
Interaction of the Eukaryotic Initiation Factor 4E with 4E-BP2 at a Dynamic Bipartite Interface
Sabelo Lukhele et al.
STRUCTURE (2013)
Structural Insights into RIP3-Mediated Necroptotic Signaling
Tian Xie et al.
CELL REPORTS (2013)
The RIP1/RIP3 Necrosome Forms a Functional Amyloid Signaling Complex Required for Programmed Necrosis
Jixi Li et al.
CELL (2012)
Arginine methylation by PRMT1 regulates nuclear-cytoplasmic localization and toxicity of FUS/TLS harbouring ALS-linked mutations
Miranda L. Tradewell et al.
HUMAN MOLECULAR GENETICS (2012)
Structures of the HIN Domain: DNA Complexes Reveal Ligand Binding and Activation Mechanisms of the AIM2 Inflammasome and IFI16 Receptor
Tengchuan Jin et al.
IMMUNITY (2012)
Interactions via intrinsically disordered regions: What kind of motifs?
Rita Pancsa et al.
IUBMB LIFE (2012)
Attributes of short linear motifs
Norman E. Davey et al.
MOLECULAR BIOSYSTEMS (2012)
Fuzziness: linking regulation to protein dynamics
Monika Fuxreiter
MOLECULAR BIOSYSTEMS (2012)
Tissue-Specific Alternative Splicing Remodels Protein-Protein Interaction Networks
Jonathan D. Ellis et al.
MOLECULAR CELL (2012)
Tissue-Specific Splicing of Disordered Segments that Embed Binding Motifs Rewires Protein Interaction Networks
Marija Buljan et al.
MOLECULAR CELL (2012)
Phase transitions in the assembly of multivalent signalling proteins
Pilong Li et al.
NATURE (2012)
Linear motifs confer functional diversity onto splice variants
Robert J. Weatheritt et al.
NUCLEIC ACIDS RESEARCH (2012)
Transient structure and dynamics in the disordered c-Myc transactivation domain affect Bin1 binding
Cecilia Andresen et al.
NUCLEIC ACIDS RESEARCH (2012)
The Acidic Transcription Activator Gcn4 Binds the Mediator Subunit Gal11/Med15 Using a Simple Protein Interface Forming a Fuzzy Complex
Peter S. Brzovic et al.
MOLECULAR CELL (2011)
Evolution of a derived protein-protein interaction between HoxA11 and Foxo1a in mammals caused by changes in intramolecular regulation
Kathryn J. Brayer et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2011)
Dynamic protein-DNA recognition: beyond what can be seen
Monika Fuxreiter et al.
TRENDS IN BIOCHEMICAL SCIENCES (2011)
Molecular Basis for Association of PIPKIγ-p90 with Clathrin Adaptor AP-2
Nina Kahlfeldt et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2010)
Expansion of the eukaryotic proteome by alternative splicing
Timothy W. Nilsen et al.
NATURE (2010)
Two Distinct Mechanisms for Actin Capping Protein Regulation-Steric and Allosteric Inhibition
Shuichi Takeda et al.
PLOS BIOLOGY (2010)
Linking folding and binding
Peter E. Wright et al.
CURRENT OPINION IN STRUCTURAL BIOLOGY (2009)
Internal Regulatory Interactions Determine DNA Binding Specificity by a Hox Transcription Factor
Ying Liu et al.
JOURNAL OF MOLECULAR BIOLOGY (2009)
The unfolded protein response signals through high-order assembly of Ire1
Alexei V. Korennykh et al.
NATURE (2009)
The Origin of Allosteric Functional Modulation: Multiple Pre-existing Pathways
Antonio del Sol et al.
STRUCTURE (2009)
Binding of the proline-rich segment of myelin basic protein to SH3 domains: Spectroscopic, microarray, and Modeling studies of ligand conformation and effects of posttranslational modifications
Eugenia Polverini et al.
BIOCHEMISTRY (2008)
Flexible nets: disorder and induced fit in the associations of p53 and 14-3-3 with their partners
Christopher J. Oldfield et al.
BMC GENOMICS (2008)
Structure of the dual enzyme ire1 reveals the basis for catalysis and regulation in nonconventional RNA splicing
Kenneth P. K. Lee et al.
CELL (2008)
Multiple intrinsically disordered sequences alter DNA binding by the homeodomain of the Drosophila Hox protein Ultrabithorax
Ying Liu et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2008)
Role of intrinsic flexibility in signal transduction mediated by the cell cycle regulator, p27Kip1
Charles A. Galea et al.
JOURNAL OF MOLECULAR BIOLOGY (2008)
Alternative isoform regulation in human tissue transcriptomes
Eric T. Wang et al.
NATURE (2008)
Malleable machines take shape in eukaryotic transcriptional regulation
Monika Fuxreiter et al.
NATURE CHEMICAL BIOLOGY (2008)
Dynamic equilibrium engagement of a polyvalent ligand with a single-site receptor
Tanja Mittag et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2008)
Fuzzy complexes: polymorphism and structural disorder in protein-protein interactions
Peter Tompa et al.
TRENDS IN BIOCHEMICAL SCIENCES (2008)
Dynamic personalities of proteins
Katherine Henzler-Wildman et al.
NATURE (2007)
Intrinsic disorder as a mechanism to optimize allosteric coupling in proteins
Vincent J. Hilser et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2007)
Differential distribution of the Mecp2 splice variants in the postnatal mouse brain
Joanna M. Dragich et al.
JOURNAL OF COMPARATIVE NEUROLOGY (2007)
Disorder and sequence repeats in hub proteins and their implications for network evolution
Zsuzsanna Dosztanyi et al.
JOURNAL OF PROTEOME RESEARCH (2006)
Structural basis for the phosphorylation-regulated focal adhesion targeting of type Iγ phosphatidylinositol phosphate kinase (PIPKIγ) by talin
Xiangming Kong et al.
JOURNAL OF MOLECULAR BIOLOGY (2006)
Conformational diversity in the TPR domain-mediated interaction of protein phosphatase 5 with Hsp90
MJ Cliff et al.
STRUCTURE (2006)
Variable control of Ets-1 DNA binding by multiple phosphates in an unstructured region
MA Pufall et al.
SCIENCE (2005)
Structural insights into a yeast prion illuminate nucleation and strain diversity
R Krishnan et al.
NATURE (2005)
A signalling pathway controlling c-Myc degradation that impacts oncogenic transformation of human cells
E Yeh et al.
NATURE CELL BIOLOGY (2004)
Mechanism of phosphorylation-dependent binding of APC to β-catenin and its role in β-catenin degradation
NC Ha et al.
MOLECULAR CELL (2004)
Biophysical properties of regions flanking the bHLH-Zip motif in the p22 Max protein
SE Pursglove et al.
BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS (2004)
Preformed structural elements feature in partner recognition by intrinsically unstructured proteins
M Fuxreiter et al.
JOURNAL OF MOLECULAR BIOLOGY (2004)
Recruitment and regulation of phosphatidylinositol phosphate kinase type 1γ by the FERM domain of talin
G Di Paolo et al.
NATURE (2002)
Share Paper
