Journal
FEBS JOURNAL
Volume 284, Issue 7, Pages 1040-1044Publisher
WILEY
DOI: 10.1111/febs.14004
Keywords
Alzheimer's disease; amyloid; APP; Down syndrome; genetics
Categories
Funding
- MRC [MR/K01417X/1, G0701075, G0901254, G1001253, MR/J004758/1] Funding Source: UKRI
- Medical Research Council [MR/L501542/1, MR/K01417X/1, G0701075, G1001253, G0901254, MR/J004758/1] Funding Source: Medline
- Parkinson's UK [G-1307] Funding Source: Medline
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The cloning of APP and genetic analysis of families with Alzheimer's disease were both reported in 1987 and much present work on the disease is based upon the foundations laid at that time. Progress was not smooth, however, and many errors were made. In this memoir, I lay out both the progress and the errors.
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